Author: John Murphy, M.D. CEO Covid-19 Long-haul Foundation Abstract Messenger RNA (mRNA) vaccines have revolutionized infectious disease prevention, offering rapid deployment and robust immunogenicity. However, emerging evidence suggests that the […]
Microclot Formation and Fibrinolytic Resistance in Long COVID: Mechanisms, Biomarkers, and Visualization
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as a chronic multisystem condition affecting millions globally. Among its most […]
Genomic Convergence: Emerging Pathways, Mechanisms, and Druggable Targets in Precision Medicine for COVID Long-haul Research
Author: John Murphy, CEO COVID-19 Long-haul Foundation Abstract The past three years have witnessed an unprecedented acceleration in genomic discovery, driven by advances in single-cell sequencing, spatial transcriptomics, and integrative […]
🧬 Spike Protein Modifications: Scientific Possibilities
If a scientist were hypothetically attempting to modify the SARS-CoV-2 spike protein for enhanced function—whether for research, vaccine design, or malicious intent—there are specific genomic regions and tools they might […]
🧠 Neurovascular Dysregulation and Cognitive Impairment in Long COVID
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), presents with a constellation of neurological symptoms including brain fog, memory loss, and […]
Post-Spike Syndrome and Spikeopathy: Central Mechanisms in Long COVID Pathophysiology
Author: John Murphy, President COVID 19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as a multifaceted syndrome affecting millions globally. While initial hypotheses […]
🧠 Neurovascular Dysregulation and Microclot Persistence in COVID-19 Long-Haul Illnesses
Author: John Murphy, President, COVID-19 Long-haul Foundation 📑 Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), affects millions globally and presents with persistent symptoms including fatigue, cognitive dysfunction, […]
Diagnostic Biomarkers and Imaging Modalities in Long COVID: Toward Precision Detection and Monitoring
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), presents with a complex array of symptoms affecting multiple organ systems. Accurate diagnosis […]
Therapeutic Strategies and Clinical Trials in Long COVID: Anticoagulants, Fibrinolytics, Endothelial Support, Immunomodulators, and RECOVER Protocols
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is a chronic multisystem condition affecting millions globally. Despite its prevalence, therapeutic options […]
Neuroinflammatory and Glutamatergic Dysregulation in Long COVID: Treating Brain Fog, Confusion, and Depression
John Murphy, – President, COVID-19 Long-haul Foundation Pathophysiology of Long COVID Neurocognitive Sequelae Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is increasingly recognized as a chronic, multisystemic condition […]