John Murphy, CEO The COVID-19 Long-haul Foundation Abstract Post-acute sequelae of SARS-CoV-2 infection (PASC), commonly termed Long COVID, is increasingly recognized as a multisystem condition characterized by fatigue, exertional intolerance, […]
COVID-19 and the Motor–Sensory Brain: Pathobiology, Microvascular Injury, Neurophysiology, Clinical Manifestations, Therapeutic Strategies, and Long-Term Outcomes
John Murphy, CEO COVID-19 Long-haul Founndation Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), initially characterized as a respiratory pathogen, is now recognized as a systemic vascular and neurotropic disease […]
Entangled in the Aftermath: Microclots, Neutrophil Traps, and the Pathophysiology of Long COVID
By John Murphy I. Prelude to Persistence In the quiet aftermath of viral storm, where acute fevers have cooled and coughs have faded into memory, a more insidious affliction lingers. […]
Microclot Formation and Fibrinolytic Resistance in Long COVID: Mechanisms, Biomarkers, and Visualization
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as a chronic multisystem condition affecting millions globally. Among its most […]
COVID Research Gaps and Future Directions: Standardization, Longitudinal Recovery, AI-Driven Biomarkers, and Policy Reform
Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), remains a poorly defined and under-researched condition affecting millions globally. Despite its prevalence, […]
Why Long COVID Causes Shortness of Breath—and What We’re Learning to Do About It
Author: John Murphy Affiliation: COVID-19 Long-haul Foundation 🌬️ Introduction: When Breathing Doesn’t Bounce Back For many people recovering from COVID-19, the virus doesn’t simply go away. Weeks or months later, […]
🦠 Long COVID and Urinary Tract Infections (UTIs): 2025 Insights into Etiology, Symptoms, Progression, and Renal Complications
Emerging 2025 research reveals a compelling link between Long COVID and urinary tract infections (UTIs), with implications for kidney damage, bladder dysfunction, and chronic urinary symptoms. This article synthesizes findings […]
Blood clotting discovery opens “whole new chapter in vascular biology”
By Paul McClure Researchers have identified a previously unknown biological process that causes tissue and organ damage in conditions where oxygen is low, such as heart attacks and strokes. The study […]
Immune damage in Long Covid
Links between the complement and coagulation systems could lead to Long Covid therapies WOLFRAM RUF Authors Info & Affiliations, SCIENCE, 18 Jan 2024, Vol 383, Issue 6680, pp. 262-263, DOI: 10.1126/science.adn1077, BY CARLO CERVIA-HASLER, SARAH C. […]