NIH-funded study finds cases of ME/CFS increase following SARS-CoV-2

Brain Fog / Fatigue / Long-haul Disease / Long-term Effects / ME/CFS Posted on: September 22, 2025June 16, 2025

NIH-funded study finds cases of ME/CFS increase following SARS-CoV-2

New findings from the National Institutes of Health’s (NIH) Researching COVID to Enhance Recovery (RECOVER) Initiative suggest that infection with SARS-CoV-2, the virus that causes COVID-19, may be associated with […]

Autonomic nervous system disruption / Chronic Fatigue / Fatigue / Immune dysregulation / Long-haul Disease / Malaise-Fatigue / ME/CFS / Microvascular damage / Mitochondrial dysfunction / Viral persistence Posted on: September 4, 2025August 30, 2025

The Lingering Pandemic: Mapping the Arc of Long COVID and the Search for Recovery

By John Murphy, The COVID 19 Long-haul Foundation Introduction: A Pandemic That Didn’t End When the world first confronted SARS-CoV-2 in early 2020, the prevailing narrative was one of acute […]

Animal Models / Depression & Mental Health / Fatigue / Long-haul Disease / Long-term Effects / Mitochondria / Mitochondrial Effects / Neuroinflammation / Neurologic Effects / Sex Related Outcome Posted on: August 29, 2025August 28, 2025

Long COVID and brain inflammation: unravelling mechanisms and potential therapies

Fatemeh Saheb Sharif-Askari1,2*†Jacob Raber3*†Karem H. Alzoubi1,2 Patients with Long COVID often experience persistent brain-related symptoms, including brain fog, mood changes, and dizziness (1–3), likely driven by neuroinflammation even after the […]

Allergic Rhinitis / Brain Fog / Chronic Fatigue Syndrome / Fatigue / Fatigue / Inflammation / Malaise-Fatigue / Nasal Congestion / Orthostatic intolerance / Shortness of Breath / Sinusitis / Smell & Taste / Taste & Smell / Taste & Smell Disturbance Posted on: August 5, 2025August 2, 2025

🩺 Chronic Sinusitis and COVID Long-Haul: A Clinical Narrative

In the evolving landscape of respiratory and post-viral illnesses, two conditions have emerged as persistent and often debilitating: Chronic Sinusitis and COVID Long-Haul Syndrome. Though distinct in origin, both share […]

Brain / Brain Fog / Chronic Fatigue Syndrome / Fatigue / Hypoxia / Malaise-Fatigue / Memory / Memory Deficit Posted on: August 4, 2025August 2, 2025

COVID-19 Prolonged Cognitive Fatigue: A Comparison With Persistent Post-concussion Symptoms

David S. Oakley • Mo Mortazavi • Daniella K. Rivera • et. al., DOI: 10.7759/cureus.88160 Abstract Introduction: Brain fog and cognitive dysfunction are frequently reported in post-viral fatigue syndromes such as long COVID, yet these symptoms remain […]

Acute Respiratory Syndrome / Brain Fog / COVID-19 / Epidemiology / Fatigue / Influenza / Long-haul Disease / Respiration / Symptoms Posted on: August 1, 2025July 28, 2025

CDC Releases Update On ‘Long COVID’ Symptoms

Authored by Jack Phillips via The Epoch Times, The U.S. Centers for Disease Control and Prevention issued an update on July 24 urging health care providers and public health officials […]

Brain / Fatigue / Immune System / Pain / Sleep Disturbance Posted on: July 31, 2025July 28, 2025

Neurological and Immunological Insights Into Post-COVID-19 Syndrome: A Single-Center Retrospective Study

Lara Diem • Simona Daepp • Vincenzo P. Introcaso • et. al., DOI: 10.7759/cureus.88098 Abstract Introduction Following the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), post-COVID-19 syndrome (PCS) has emerged as a […]

Circadian Rhythm / Fatigue / Hypersomnia / Narcolepsy / Sleep & Dreams / Sleep Disturbance Posted on: July 24, 2025July 21, 2025

🧬 Mechanisms of Action Behind COVID-Induced Hypersomnia

Hypersomnia, or excessive daytime sleepiness (EDS), has emerged as a notable neurological complication in some individuals following SARS-CoV-2 infection, particularly in the context of Long COVID. While fatigue is more […]

Fatigue / Long-haul Disease / Long-term Effects / Myalgia-Muscle Pain Posted on: July 20, 2025May 1, 2025

Long COVID: A living systematic review

BMJ 2024; 387 doi: https://doi.org/10.1136/bmj-2024-081318, Cite this as: BMJ 2024;387:e081318 Abstract Objective To compare the effectiveness of interventions for the management of long covid (post-covid condition). Design Living systematic review. Data sources Medline, Embase, CINAHL, PsycInfo, Allied and Complementary […]

Brain / Brain Fog / Cytokine Storm / Fatigue / Glymphatic system / IL-6 / Inflammation / Neuroinflammation / Neuropathy / Sleep & Dreams / Sleep Disturbance / TNF alpha / TNFα Posted on: July 15, 2025July 11, 2025

Sudden Sleep Collapse: A Long-COVID Nightmare

Long COVID can trigger sudden collapses in consciousness or overwhelming sleepiness through a mix of neurological, immunological, and autonomic dysfunctions. Here’s how the body gets hijacked into shutdown mode: 🧠 […]