Elevated clotting factor V levels linked to worse outcomes in severe COVID-19 infections

Clots & Bleeds / coagulopathy / COVID-19 Associated Coagulopathy / Factor V Posted on: March 8, 2022

Elevated clotting factor V levels linked to worse outcomes in severe COVID-19 infections

Authors: Jonathan A. Stefely,Bianca B. Christensen,Tasos Gogakos,Jensyn K. Cone Sullivan … See all authors First published: 24 August 2020 https://doi.org/10.1002/ajh.25979 Abstract Coagulopathy causes morbidity and mortality in patients with coronavirus disease 2019 (COVID-19) due […]

Clots & Bleeds / Coagulation / coagulopathy / COVID-19 Associated Coagulopathy / Treatments Posted on: March 7, 2022

Nuts and bolts of COVID-19 associated coagulopathy: the essentials for management and treatment

Authors: Patrick J Lindsay, a Rachel Rosovsky, b Edward A Bittner, c and Marvin G. Chang c ABSTRACT Introduction COVID-19-associated coagulopathy (CAC) is a well-recognized hematologic complication among patients with severe COVID-19 disease, where macro- and micro-thrombosis can […]

Clots & Bleeds / Coagulation / coagulopathy / Factor VII / Protein C Posted on: March 7, 2022

Factor VIII and Functional Protein C Activity in Critically Ill Patients With Coronavirus Disease 2019: A Case Series

Ali Tabatabai 1, Joseph Rabin 2, Jay Menaker 2, Ronson Madathil 3, Samuel Galvagno 4, Ashley Menne 5, Jonathan H Chow 4, Alison Grazioli 6, Daniel Herr 1, Kenichi Tanaka 4, Thomas Scalea 2, Michael Mazzeffi 4Affiliations expand PMID: 32539272 PMCID: PMC7242090 DOI: 10.1213/XAA.0000000000001236 Abstract Critically ill patients with coronavirus disease 2019 (COVID-19) have been observed to […]

Clots & Bleeds / Coagulation / coagulopathy / COVID-19 Associated Coagulopathy / Genomics / Risk Factors / Sequence Posted on: March 7, 2022

Whole genome sequencing reveals host factors underlying critical Covid-19

Authors: Athanasios Kousathanas, Erola Pairo-Castineira, J. Kenneth BaillieArticle Published: 07 March 2022 nature articles article We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the […]

Chilblains / Clots & Bleeds / Finger's / Foot / Toes / Wound Care Posted on: February 9, 2022

A Review of COVID-19 Chilblains-like Lesions and Their Differential Diagnoses

Authors: Sachdeva, Muskaan BHSc; Mufti, Asfandyar MD, BMSc; Maliyar, Khalad BA; Lara-Corrales, Irene MD, MSc; Salcido, Richard MD, EdD, FAAPMR; Sibbald, Cathryn MD, FRCPC Abstract GENERAL PURPOSE To familiarize wound […]

Altered Mental State / Attention Deficit / Brain / Brain Fog / Clots & Bleeds / Cognitive Deficits / Confusion / Dementia / Depression & Mental Health / Dizziness / Headache / Ischemic Stroke / Long-haul Disease / Long-term Effects / Memory Deficit / Nerve Cell Injury / Stroke / TIA Posted on: February 5, 2022

6-month neurological and psychiatric outcomes in 236,379 survivors of COVID-19: a retrospective cohort study using electronic health records

Authors: Maxime Taquet, John R Geddes, Masud Husain, Sierra Luciano, Paul J Harrison Summary Background Neurological and psychiatric sequelae of COVID-19 have been reported, but more data are needed to […]

Clots & Bleeds / coagulopathy / Deep Vein Thrombosis / Endothelium / Heparin / Peripheral Vessels / Spike Protein / Thrombosis / Treatments / Vascular System Posted on: February 3, 2022

COVID‐19‐induced endotheliitis: emerging evidence and possible therapeutic strategies

Authors: Eleonora Calabretta, 1 , 12 Jose M. Moraleda, 2 Massimo Iacobelli, 3 Ruben Jara, 4 Israel Vlodavsky, 5 Peter O’Gorman, 6 Antonio Pagliuca, 7 Clifton Mo, 8 Rebecca M. Baron, 9 Alessio Aghemo, 10 , 12 Robert Soiffer, 8 Jawed Fareed, 11 Carmelo Carlo‐Stella, 1 , 12 , * and Paul Richardson 8 , * Br J Haematol. 2021 Apr; 193(1): 43–51.Published online […]

Clots & Bleeds / coagulopathy / COVID-19 Associated Coagulopathy / D-dimer / Endothelium / Long-haul Disease / P-selectin / Vascular System / von Willebrand Factor / Weibel–Palade bodies Posted on: February 1, 2022

The coagulopathy, endotheliopathy, and vasculitis of COVID-19

Authors: Toshiaki Iba 1, Jean Marie Connors 2, Jerrold H Levy 3 PMID: 32918567 PMCID: PMC7486586 DOI: 10.1007/s00011-020-01401-6 Abstract Background COVID-19-associated coagulopathy (CAC) characterized by the elevated D-dimer without remarkable changes of other global coagulation markers is associated […]

Clots & Bleeds / coagulopathy / COVID-19 Associated Coagulopathy / Disseminated Intravascular Coagulation / Endothelium / Hemorrhage / P-selectin / von Willebrand Factor Posted on: February 1, 2022

COVID-19-associated coagulopathy: An exploration of mechanisms

Authors: Meaghan E Colling 1, Yogendra Kanthi 2 PMID: 32558620 PMCID: PMC7306998 OI: 10.1177/1358863X20932640 Abstract An ongoing global pandemic of viral pneumonia (coronavirus disease [COVID-19]), due to the virus SARS-CoV-2, has infected millions of people and […]

Clots & Bleeds / Coagulation / coagulopathy / COVID-19 Associated Coagulopathy / D-dimer / Endothelium / P-selectin / von Willebrand Factor Posted on: February 1, 2022

Role of von Willebrand Factor in COVID-19 Associated Coagulopathy

Authors: Zhen W Mei, Xander M R van Wijk, Huy P Pham, Maximo J Marin The Journal of Applied Laboratory Medicine, Volume 6, Issue 5, September 2021, Pages 1305–1315, https://doi.org/10.1093/jalm/jfab042Published: 13 June 2021 Abstract […]