More than 50 long-term effects of COVID-19: a systematic review and meta-analysis

Sandra Lopez-Leon, Talia Wegman-Ostrosky, Nature Scientific Reports volume 11, Article number: 16144 (2021)  Abstract COVID-19 can involve persistence, sequelae, and other medical complications that last weeks to months after initial recovery. This systematic review and meta-analysis aims to identify studies assessing the long-term effects of COVID-19. LitCOVID and Embase were searched to identify articles with original data published before the 1st […]

Treatment with stimulants and the risk of COVID-19 complications in adults with ADHD

Wen-Jan Tuan,a,⁎ Dara E. Babinski,b David P. Rabago,a,b,c and Aleksandra E. Zgierskac Abstract Adults with attention deficit hyperactivity disorder (ADHD) have shown higher infection rates and worse outcomes from COVID-19. Stimulant medications are prescribed as the first-line treatment for ADHD in adults and mitigate risk of negative ADHD-related health outcomes, but little is known about the association between stimulant […]

Ritalin (Methylphenidate) For Chronic Fatigue Syndrome and Fibromyalgia

Methylphenidate (Ritalin, Concerta) Ritalin Is… a central nervous system stimulant. Created in 1954, Ritalin has been in use for over sixty years. (Check out a History of Ritalin here). It was first FDA approved in 1955 to treat ‘hyperactivity’ and later was approved to treat attention deficit hyperactivity disorder (ADHD). Ritalin increases extracellular levels of dopamine […]

New research helps explain how Ritalin sharpens attention

Date: April 29, 2022 Source: University of Pittsburgh Science Daily Summary: Researchers found animals that had taken methylphenidate performed better on a visual task of attention, and that the improvement happened exactly when that same metric of neuron activity shifted. Even half a century after a drug comes on the market, scientists can still learn […]

7 in 10 long COVID patients are dealing with memory and concentration problems

Authors: Study Finds MARCH 17, 2022 The vast majority of people dealing with “long COVID” are experiencing memory and concentration problems — months after their actual coronavirus infection, a new study warns. Researchers at the University of Cambridge say seven in 10 people experiencing the lingering effects of COVID are now struggling mentally. The study […]

6-month neurological and psychiatric outcomes in 236,379 survivors of COVID-19: a retrospective cohort study using electronic health records

Authors: Maxime Taquet, John R Geddes, Masud Husain, Sierra Luciano, Paul J Harrison Summary Background Neurological and psychiatric sequelae of COVID-19 have been reported, but more data are needed to adequately assess the effects of COVID-19 on brain health. We aimed to provide robust estimates of incidence rates and relative risks of neurological and psychiatric […]

Multiple Early Factors Anticipate Post-Acute COVID-19 Sequelae

Authors: Yapeng Su 28, Dan Yuan 28, Daniel G. Chen 28,Mark M. Davis, Jason D. Goldman, James R. Heath 29 Highlights Longitudinal multiomics associate PASC with autoantibodies, viremia and comorbidities Reactivation of latent viruses during initial infection may contribute to PASC Subclinical autoantibodies negatively correlate with anti-SARS-CoV-2 antibodies Gastrointestinal PASC uniquely present with post-acute expansion of cytotoxic T cells […]

More than 50 Long-Term Effects of COVID-19: A Systematic Review and Meta-Analysis

Authors: López-León S, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo PA, Cuapio A, Villapol S Preprint from SSRN, 20 Jan 2021 Abstract  Background: COVID-19, caused by SARS-CoV-2, can involve sequelae that last weeks to months after initial recovery. The objective of this systematic review and meta-analysis is to identify studies assessing the long-term effects of COVID-19 and estimate the prevalence of each symptom, […]