Cutting Edge: Hyperinflammatory Monocytes Expressing CD56 Abound in Severe COVID-19 Patients 

Stefania Campana; Claudia De Pasquale; Giacomo Sidoti Migliore;, et. al. J Immunol (2022) 209 (4): 655–659. https://doi.org/10.4049/jimmunol.2200021 Abstract Proinflammatory monocytes play a preponderant role in the development of a cytokine storm…[...]

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Endothelial cell damage is the central part of COVID-19 and a mouse model
induced by injection of the S1 subunit of the spike protein

Authors: Gerard J. NuovoCynthia MagroToni ShafferHamdy AwadDavid SusterSheridan MikhailBing HeJean-Jacques MichailleBenjamin LiechtyEsmerina Tili Annals of Diagnostic Pathology ABS T R A C TNeurologic complications of symptomatic COVID-19 are common. Brain…[...]

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IL-13 decreases susceptibility to airway epithelial SARS-CoV-2 infection but increases disease severity in vivo

Shreya Ghimire, Biyun Xue, Kun Li, Ryan M Gannon, et. al.doi: https://doi.org/10.1101/2024.07.03.60194 Abstract Treatments available to prevent progression of virus-induced lung diseases, including coronavirus disease 2019 (COVID-19) are of limited benefit once respiratory failure occurs. The efficacy of approved…[...]

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The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches

Roxana Gheorghita1,2Iuliana Soldanescu3Andrei Lobiuc2 , et. al., Front. Immunol., 03 March 2024, Sec. Viral Immunology, Volume 15 - 2024 | https://doi.org/10.3389/fimmu.2024.1344086 The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has…[...]

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Pathophysiological, immunological, and inflammatory features of long COVID

Karen Bohmwald1,2†Benjamín Diethelm-Varela1†Linmar Rodríguez-Guilarte1 , et. al., Front. Immunol., 27 February 2024, Sec. Viral Immunology, Volume 15 - 2024 | https://doi.org/10.3389/fimmu.2024.1341600 The COVID-19 pandemic continues to cause severe global disruption, resulting…[...]

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Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection

Chansavath Phetsouphanh, Brendan Jacka, et. al., Nature Communications volume 15, Article number: 3315 (2024) Abstract This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long…[...]

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Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

Suo-wen Xu, Iqra Ilyas & Jian-ping Weng  Acta Pharmacologica Sinica volume 44, pages695–709 (2023) Cite this article 17 October 2022 Abstract The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is still raging. However,…[...]

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COVID-19 can trigger auto-immune disorders-related antibodies, causing thrombosis and other complications

SEPTEMBER 12, 2023 by Maria Fernanda Ziegler, FAPESP Medical Express The systems immunology approach identifies an aging effect on autoantibody levels of COVID-19 patients. Credit: npj Aging (2023). DOI: 10.1038/s41514-023-00118-0 An article published in npj Aging reveals…[...]

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