Category: Serotonin

What do we know about covid-19’s effects on the brain?

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BMJ 2024; 385 doi: https://doi.org/10.1136/bmj.q897 (Published 15 May 2024)Cite this as: BMJ 2024;385:q897 What are the neurological symptoms of covid-19? Covid may be primarily a respiratory infection, but a common symptom is “brain fog”—problems with memory or concentration—which can persist for weeks or months as part of long covid.1 And it’s not the only neurological effect. Giovanni Schifitto, professor of neurology at the […]

Evaluation of Post–COVID-19 Cognitive Dysfunction: Recommendations for Researchers

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Jaqueline H. Becker, PhD1; Tracy D. Vannorsdall, PhD2; Sara L. Weisenbach, PhD3, JAMA Psychiatry. 2023;80(11):1085-1086. doi:10.1001/jamapsychiatry.2023.2820 SARS-CoV-2 infection is associated with increased rates of postillness cognitive dysfunction, colloquially referred to as “brain fog,”1 that may portend significant consequences for patient functioning and quality of life. Post–COVID-19 cognitive dysfunction is 1 of approximately 200 symptoms of post–COVID-19 condition (PCC), defined by the World Health Organization as […]

Long COVID Linked With Viral Persistence, Serotonin Decline

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Emily Harris, JAMA. Published online November 1, 2023. doi:10.1001/jama.2023.21170 A study linking viral infection with reduced levels of serotonin, a neurotransmitter involved in learning, memory, and mood, has proposed a new potential mechanism underlying post–COVID-19 condition. Also known as long COVID, the condition involves symptoms such as fatigue, memory loss, and cognitive impairment. Using results from human participants, […]

Serotonin reduction in post-acute sequelae of viral infection

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Andrea C. Wong, Ashwarya S. Devason, Iboro C. Umana, Sara Cherry, Christoph A. Thaiss, Maayan Levy 2Open Access Published:October 16, 2023DOI:https://doi.org/10.1016/j.cell.2023.09.013 Cell VOLUME 186, ISSUE 22, P4851-4867.E20, OCTOBER, 2023 Highlights Summary Post-acute sequelae of COVID-19 (PASC, “Long COVID”) pose a significant global health challenge. The pathophysiology is unknown, and no effective treatments have been found to date. Several […]