Role of von Willebrand Factor in COVID-19 Associated Coagulopathy


Authors: Zhen W Mei, Xander M R van Wijk, Huy P Pham, Maximo J Marin The Journal of Applied Laboratory Medicine, Volume 6, Issue 5, September 2021, Pages 1305–1315,  https://doi.org/10.1093/jalm/jfab042Published: 13 June 2021 Abstract…[...]

Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition


Authors: Jia Yu, Xuan Yuan, Hang Chen, Shruti Chaturvedi, Evan M. Braunstein, Robert A. Brodsky Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious respiratory virus that can lead to venous/arterial thrombosis, stroke,…[...]

Never ignore extremely elevated D-dimer levels: they are specific for serious illness


Authors: T Schutte 1, A Thijs, Y M Smulders D-dimer is routinely measured as part of the clinical diagnosis algorithms for venous thromboembolism (VTE). In these algorithms, low D- dimer cut-off values are…[...]