A Clinical Review of Diarrhea, Constipation, Reflux, and Abdominal Pain John Murphy. CEO COVID 19 Long-haul Foundation PART I: Epidemiology, Phenotypes, and Pathophysiological Foundations Abstract (Part I focus) tGastrointestinal (GI) […]
Depression in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)
John Murphy, CEO Covid19 Long-haul Foundation A Comprehensive Review of Long-COVID–Associated Depressive Disorders Abstract Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), commonly known as Long COVID, has emerged as one of […]
Long COVID and Sleep Disorders: An Emerging Biologic Nexus in Post-Acute Sequelae of SARS-CoV-2 Infection
John Murphy, CEO, COVID-19 Long-haul Foundation Abstract Sleep disturbance has emerged as one of the most prevalent, persistent, and disabling manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), commonly known […]
Long COVID and Dysautonomia
John Murphy, M.D., M.P.H., D.P.H., President, The COVID-19 Lonh-haul Foundation Abstract: Long COVID (post-acute sequelae of SARS-CoV-2 infection, PASC) is increasingly recognized as a heterogeneous syndrome characterized by persistent fatigue, […]
Peripheral Sensory Dysfunction in Long COVID: Etiology, Genomics, Pathophysiology, Clinical Manifestations, Diagnostic Approaches, Disease Progression, and Long-Term Outcomes
John Murphy, MD., M.P.H., D.P.H., CEO, COVID-19 long-haul Foundation Abstract Long COVID, also known as Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), has emerged as one of the most significant chronic […]
Long-COVID Brain Fog: Reconsidering the Centrality of Ongoing Neuroinflammation
A Mechanistic Reappraisal of Cognitive Dysfunction Following SARS-CoV-2 Infection Author: John Murphy, CEO, COVID-19 Long-haul Foundation Abstract “Brain fog” in Long COVID has often been attributed to persistent neuroinflammation driven […]
COVID-19 and Loss of Sensory-motor Function
John Murphy, CEO Covid 10 Long-haul Foundationn Loss of sensory-motor function affecting the hands, arms, legs, and feet has become one of the more disabling neurological manifestations reported after acute […]
COVID-19 and the Motor–Sensory Brain: Pathobiology, Microvascular Injury, Neurophysiology, Clinical Manifestations, Therapeutic Strategies, and Long-Term Outcomes
John Murphy, CEO COVID-19 Long-haul Founndation Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), initially characterized as a respiratory pathogen, is now recognized as a systemic vascular and neurotropic disease […]
NIH RECOVER Clinical Trials and the First Emergence of Interventional Results in Long COVID Research: A Translational Turning Point
A Scholarly Review for Scientific American (Submission-Style Manuscript) John Murphy, M.D., M.P.H., D.P.H., President, COVID-19 Long-Haul Foundation Abstract The NIH RECOVER Initiative represents the largest coordinated research program investigating post–acute […]
Recognition of Long COVID as a Heterogeneous Post-Infectious Syndrome
Toward a Multisystem Endotype Framework for Post–Acute SARS-CoV-2 Disease John Murphy, M.D., M.P.H., D.P.H. President Covid-19 Long-haul Foundation Abstract Long COVID (post–acute sequelae of SARS-CoV-2 infection, PASC) has emerged as […]