Authors: Alessandro Sette 1 2, Shane Crotty 3 4 Abstract T cell reactivity against SARS-CoV-2 was observed in unexposed people; however, the source and clinical relevance of the reactivity remains unknown. It is speculated that […]
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19) – anatomic pathology perspective on current knowledge
Authors: Sambit K. Mohanty, Abhishek Satapathy, Machita M. Naidu, Sanjay Mukhopadhyay, Shivani Sharma, Lisa M. Barton, Edana Stroberg, Eric J. Duval, Dinesh Pradhan, Alexandar Tzankov & Anil V. Parwani Abstract Background The world is currently witnessing a major devastating pandemic of […]
What Does COVID Do to Your Blood?
Authors: Panagis Galiatsatos, M.D., M.H.S., Robert Brodsky, M.D. COVID-19 is a very complex illness. The coronavirus that causes COVID-19 attacks the body in many different ways, ranging from mild to […]
How To Increase Platelet Count In COVID Patients? What Is Thrombocytopenia?
Authors: Ananya Varma Platelets are said to play an important role in inflammatory signalling. Here is why it is important to keep a check of Platelet count in COVID patients. Given […]
Thrombocytopenia following Pfizer and Moderna SARS‐CoV‐2 vaccination
Authors: Eun‐Ju Lee, 1 Douglas B. Cines, 2 Terry Gernsheimer, 3 Craig Kessler, 4 Marc Michel, 5 Michael D. Tarantino, 6 John W. Semple, 7 Donald M. Arnold, 8 Bertrand Godeau, 5 Michele P. Lambert, 9 , 10 and James B. Bussel 11 Cases of apparent secondary immune thrombocytopenia (ITP) after SARS‐CoV‐2 vaccination […]
Platelets Promote Thromboinflammation in SARS-CoV-2 Pneumonia
Authors: Francesco Taus, Gianluca Salvagno, Stefania Canè, Cristiano Fava, Fulvia Mazzaferri, Elena Carrara, Varvara Petrova, Roza Maria Barouni, Francesco Dima, Andrea Dalbeni, Simone Romano, Abstract Objective: Pulmonary thrombosis is observed in severe acute respiratory syndrome coronavirus 2 pneumonia. Aim was […]
Platelet Gene Expression and Function in COVID-19 Patients
Authors: Bhanu Kanth Manne (University of Utah, United States) Frederik Denorme (Molecular Medicine Program, University of Utah, United States), Elizabeth Middleton (University of Utah, United States), Irina Portier (University of […]
SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19
Authors: Si Zhang 1, Yangyang Liu 2, Xiaofang Wang 2, Li Yang 3, Haishan Li 4, Yuyan Wang 5, Mengduan Liu 2, Xiaoyan Zhao 2, Youhua Xie 5, Yan Yang 6, Shenghui Zhang 7, Zhichao Fan 8, Jianzeng Dong 2, Zhenghong Yuan 5, Zhongren Ding 2, Yi Zhang 9, Liang Hu 10 Abstract Background: Critically ill patients diagnosed with COVID-19 may develop a pro-thrombotic […]
The Impact of COVID-19 Disease on Platelets and Coagulation
Authors: Geoffrey D Wool 1, Jonathan L Miller 2 Abstract Coronavirus disease 2019 (COVID-19) causes a spectrum of disease; some patients develop a severe proinflammatory state which can be associated with a unique […]
Insights into How SARS-CoV-2 Causes Brain Pathology
Authors: Anthony L. Komaroff, MD, reviewing Yang AC et al. Nature 2021 Jul Marshall M. Nature 2021 Jul In deceased COVID-19 patients, gene expression in the choroid plexus was altered. People infected with SARS-CoV-2 can […]