Category: ACE2 Receptors

COVID-19 and the liver

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Authors: Dinesh Jothimani, Radhika Venugopal,∗Mohammed Forhad Abedin, Ilankumaran Kaliamoorthy, and Mohamed Rela J Hepatol. 2020 Nov; 73(5): 1231–1240.Published online 2020 Jun 15. doi: 10.1016/j. jhep.2020.06.006PMCID: PMC7295524PMID: 32553666 Abstract The current coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become a major public health crisis over the past few months. Overall case fatality rates range between 2–6%; […]

Does COVID-19 Cause Hypertension?

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Authors: Mahmut Akpek, MD  December 10, 2021 Research Article https://doi.org/10.1177/00033197211053903 Abstract The coronavirus disease 2019 (COVID-19) outbreak remains a major public health challenge worldwide. The present study investigated the effect of COVID-19 on blood pressure (BP) during short term follow-up. A total of 211 consecutive COVID-19 patients who were admitted to Parkhayat Kutahya hospital were retrospectively screened. […]

Close relatives of MERS-CoV in bats use ACE2 as their functional receptors

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Authors: Qing Xiong,  View ORCID , , ei Cao,  Chengbao Ma,  Chen Liu, Junyu Si,  Peng Liu,  Mengxue Gu,  Chunli Wang, Lulu Shi, Fei Tong, Meiling Huang, Jing Li, Chufeng Zhao,  Chao Shen,   Yu Chen,   Huabin Zhao,  Ke Lan,  Xiangxi Wang,  Huan Yan Summary Middle East Respiratory Syndrome coronavirus (MERS-CoV) and several bat coronaviruses employ Dipeptidyl peptidase-4 (DPP4) as their functional receptors1–4. However, the receptor for NeoCoV, the closest MERS-CoV relative yet discovered in bats, remains enigmatic5. In this study, we unexpectedly found that […]

Spike Proteins, COVID-19, and Vaccines

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A new study further elucidates the role of spike proteins in COVID-19. Authors: Steven Novella  May 5, 2021 A recent study looks at the effects of the SARS-CoV-2 spike proteins, showing that they can cause some of the harm of COVID-19 by themselves. This is an important advance in our understanding of the disease and hopefully […]

‘We Made a Big Mistake’ — COVID Vaccine Spike Protein Travels From Injection Site, Can Cause Organ Damage

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Authors:  Children’s Health Defense COVID vaccine researchers had previously assumed mRNA COVID vaccines would behave like traditional vaccines. The vaccine’s spike protein — responsible for infection and its most severe symptoms — would remain mostly in the injection site at the shoulder muscle or local lymph nodes. But new research obtained by a group of scientists contradicts […]

Long-Haulers: Spike Protein Present on Covid And in Vaccines Dangerously Modifies Genes Even After Exposure – Texas Tech Uni Study

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A study by the Texas Tech University published in Biochemistry and Molecular Biology section of the FASEB journal, has found that spike proteins which Covid-19 uses to penetrate cells and is also supplied in abundance by vaccines to stimulate the body’s immune response, modify the body’s genes. The study coordinators, Nicholas Evans et al. found that even after exposure, […]

Resolving “Long-Haul COVID” and Vaccine Toxicity: Neutralizing the Spike Protein

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Authors: Dr. Thomas E. Levy, MD, JD   July 1, 2021 Although the mainstream media outlets might have you believe otherwise, the vaccines that continue to be administered for the COVID pandemic are emerging as substantial sources of morbidity and mortality themselves. While the degree to which these negative outcomes of the COVID vaccines can be […]

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

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Authors: ViewAmarendra Pegu1,†, Sarah O’Connell1,† View ORCID ProfileStephen D. Schmidt1,†, Sijy O’Dell1,†,  View ORCID ProfileChloe A. Talana1, Lilin Lai2, Jim Albert Science  12 Aug 2021: eabj4176m OI: 10.1126/science.abj4176 Abstract SARS-CoV-2 mutations may diminish vaccine-induced protective immune responses, particularly as antibody titers wane over time. Here, we assess the impact of SARS-CoV-2 variants B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma), B.1.429 (Epsilon), […]

Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people

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Julia Hippisley-Cox1, Duncan Young2,3, Carol Coupland4, Keith M Channon5, Pui San Tan6, David A Harrison7, Kathryn Rowan8,  Paul Aveyard6, Ian D Pavord9, Peter J Watkinson5,10 Correspondence to Prof Julia Hippisley-Cox, Primary Care Health Sciences, University of Oxford, Oxford OX1  Abstract Background  There is uncertainty about the associations of angiotensive enzyme (ACE) inhibitor and angiotensin receptor blocker (ARB) drugs with COVID-19 disease. We studied whether […]

Link between fever, diarrhea, severe COVID-19, and persistent anti-SARS-CoV-2 antibodies

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Authors: By Dr. Liji Thomas, MD Jan 7 2021 Ever since the coronavirus disease 2019 (COVID-19) pandemic began, there have been many attempts to understand the nature and duration of immunity against the causative agent, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A new preprint research paper appearing on the medRxiv* server describes a link between the […]