Category: Epstein Barr

Clinical Significance of CBC and WBC Morphology in the Diagnosis and Clinical Course of COVID-19 Infection 

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Olga Pozdnyakova, MD, PhD, Nathan T Connell, MD, MPH, Elisabeth M Battinelli, MD, PhD, Jean M Connors, MD, Geoffrey Fell, MS, Annette S Kim, MD, PhD, American Journal of Clinical Pathology, Volume 155, Issue 3, March 2021, Pages 364–375, https://doi.org/10.1093/ajcp/aqaa231 Abstract Objectives To investigate the clinical significance of numeric and morphologic peripheral blood (PB) changes in coronavirus disease 2019 (COVID-19)–positive patients […]

Long Covid Defined

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Authors: E. Wesley Ely, M.D., M.P.H. https://orcid.org/0000-0003-3957-2172, Lisa M. Brown, M.P.H., and Harvey V. Fineberg, M.D., Ph.D., for the National Academies of Sciences, Engineering, and Medicine Committee on Examining the Working Definition for Long Covid, DOI: 10.1056/NEJMsb2408466 The Covid-19 pandemic has been perceived mainly as a dangerous acute outbreak of infection that killed more than a million people in the United States and 7 million worldwide.1,2 However, […]

The underlying cause of Long COVID is still a puzzle

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The underlying cause of Long COVID is still a puzzle to researchers. But Akiko Iwasaki, PhD, Sterling Professor of Immunobiology and Molecular, Cellular, and Developmental Biology at Yale School of Medicine (YSM) and co-lead investigator of the Yale RECOVERY and Yale LISTEN studies, has theories. Iwasaki explains that Long COVID is an “umbrella term” and likely has “multiple mechanisms that are not […]

From Infection to Chronic Illness: Learning From Long COVID

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May 17, 2024, American Society for Microbiology Since the COVID-19 pandemic, SARS-CoV-2 has caused unexplained, chronic, post-infection symptoms in survivors. The phenomenon, known as post-acute sequelae of SARS-CoV-2 infection or “Long COVID,” surfaced shortly after COVID-19 testing was introduced to the public, and doctors began noting a pattern of onset of chronic fatigue and dysautonomia in patients […]

The Long History of Long COVID and Other Chronic Illnesses

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October 31, 2023, by Isabella Backman Yale School of Medicine Long COVID is by no means unique in causing a wide array of symptoms that persist for weeks, months, or even years after a person has recovered from the acute infection. “Post-acute infection syndromes have been going on for decades—or maybe hundreds of years—but we […]

Orthostatic Intolerance in Long-Haul COVID after SARS-CoV-2: A Case-Control Comparison with Post-EBV and Insidious-Onset Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients

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C. (Linda) M. C. van Campen* and Frans C. Visser, Kenneth J. Friedman, Academic Editor, Patricia A. Fennell, Academic Editor, Derek F. H. Pheby, Academic Editor, Evan Spivack, Academic Editor, James M. Oleske, Academic Editor, Nancy Klimas, Academic Editor, Pawel Zalewski, Academic Editor, and Susan M. Levine, Academic Editor Healthcare (Basel). 2022 Oct; 10(10): 2058. Published online 2022 Oct 17. doi: 10.3390/healthcare10102058, PMCID: PMC9602265,PMID: 36292504 Abstract Background: As complaints of long-haul […]

Potential molecular mechanisms of chronic fatigue in long haul COVID and other viral diseases

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Carl Gunnar Gottschalk, Daniel Peterson, Jan Armstrong, Konstance Knox & Avik Roy  Infectious Agents and Cancer volume 18, Article number: 7 (2023) Cite this article, A Correction to this article was published on 24 April 2023 Abstract Historically, COVID-19 emerges as one of the most devastating diseases of humankind, which creates an unmanageable health crisis worldwide. Until now, this disease costs millions of lives and continues to paralyze […]

Spinal cord involvement in COVID-19: A review

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Ravindra Kumar Garg,1 Vimal Kumar Paliwal,2 and Ankit Gupta2 J Spinal Cord Med. 2023; 46(3): 390–404. Published online 2021 Mar 11. doi: 10.1080/10790268.2021.1888022 PMCID: PMC10114972PMID: 33705268 Abstract Context: Recent literature points towards myelitis, like encephalitis, as a common central nervous system complication of COVID-19. This review elaborates on disorders of the spinal cord caused by the SARS-CoV-2 virus. Objectives: To review the published data about […]

Unraveling long COVID: Here’s what scientists who study the illness want to find out

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September 9, 2023, By Will Stone NPR Newsletter Researchers looking for root causes of long COVID work in the autopsy suite inside the Clinical Center at the National Institute of Health in Bethesda, Maryland. Valerie Plesch/Bloomberg via Getty Images For people suffering from long COVID’s often disabling symptoms, including intense fatigue, breathing troubles, cognitive issues and heart […]