Characteristics of SARS-CoV-2 and COVID-19


Authors: Ben Hu, Hua Guo, Peng Zhou & Zheng-Li Shi  Nature Reviews Microbiology volume 19, pages141–154 (2021) Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which threatens human health and public safety. In this Review, we […]

C-Reactive Protein Level May Predict the Risk of COVID-19 Aggravation


Authors: Guyi Wang 1, Chenfang Wu 1, Quan Zhang 2, Fang Wu 3, Bo Yu 1, Jianlei Lv 2, Yiming Li 4, Tiao Li 5, Siye Zhang 1, Chao Wu 6 7 8, Guobao Wu 1, Yanjun Zhong 1Affiliations expand Abstract Background: Clinical findings indicated that a fraction of coronavirus disease 2019 (COVID-19) patients diagnosed as mild early may progress to severe cases. However, it is difficult to distinguish these patients in the early stage. The present study aimed to describe the […]

Elevated level of C‐reactive protein may be an early marker to predict risk for severity of COVID‐19


Authors: Nurshad Ali 1 The outbreak of coronavirus disease‐2019 (COVID‐19) is an emerging global health threat. The healthcare workers are facing challenges in reducing the severity and mortality of COVID‐19 across the world. Severe patients with COVID‐19 are generally treated in the intensive care unit, while mild or non‐severe patients treated in the usual isolation ward […]

The role of C-reactive protein as a prognostic marker in COVID-19


Authors: Dominic Stringer,1Philip Braude,2Phyo K Myint,3Louis Evans,4Jemima T Collins,5Alessia Verduri,6Terry J Quinn,7Arturo Vilches-Moraga,8Michael J Stechman,9Lyndsay Pearce,10Susan Moug,11Kathryn McCarthy,12Jonathan Hewitt,13 and Ben Carter1 Abstract Background C-reactive protein (CRP) is a non-specific acute phase reactant elevated in infection or inflammation. Higher levels indicate more severe infection and have been used as an indicator of COVID-19 disease severity. However, the […]

Can we predict the severe course of COVID-19 – a systematic review and meta-analysis of indicators of clinical outcome?


Authors: Stephan Katzenschlager ,Alexandra J. Zimmer ,Claudius Gottschalk, Jürgen Grafeneder,Stephani Schmitz, Sara Kraker, Marlene Ganslmeier, Amelie Muth, Alexander Seitel, Lena Maier-Hein, Andrea Benedetti, Jan Larmann, Markus A. Weigand, Sean McGrath , Claudia M. Denkinger   Abstract Background COVID-19 has been reported in over 40million people globally with variable clinical outcomes. In this systematic review and meta-analysis, we assessed demographic, […]