Authors: Alessandro Sette 1 2, Shane Crotty 3 4 Abstract T cell reactivity against SARS-CoV-2 was observed in unexposed people; however, the source and clinical relevance of the reactivity remains unknown. It is speculated that […]
A long-term perspective on immunity to COVID
Determining the duration of protective immunity to infection by SARS-CoV-2 is crucial for understanding and predicting the course of the COVID-19 pandemic. Clinical studies now indicate that immunity will be […]
Use of adenovirus type-5 vectored vaccines: a cautionary tale
Authors: The Lancet We are writing to express concern about the use of a recombinant adenovirus type-5 (Ad5) vector for a COVID-19 phase 1 vaccine study,1 and subsequent advanced trials. Over […]
Pros and Cons of Adenovirus-Based SARS-CoV-2 Vaccines
Authors: Eric J. Kremer1,∗ Main Text Most of us might be surprised by the rudimentary scientific rationale prevalent in the field of vaccine research just 50 years ago. For over […]
COVID and the brain: researchers zero in on how damage occurs
Authors: Michael Marshall Growing evidence suggests that the coronavirus causes ‘brain fog’ and other neurological symptoms through multiple mechanisms. How COVID-19 damages the brain is becoming clearer. New evidence suggests […]
COVID-19 survivors may possess wide-ranging resistance to the disease
Authors: Rajee Suri rajee.suri@emory.edu Recovered COVID-19 patients retain broad and effective longer-term immunity to the disease, suggests a recent Emory University study, which is the most comprehensive of its kind […]
Covid-19 natural immunity compared to vaccine-induced immunity: The definitive summary
Authors: DATED: AUGUST 6, 2021 BY SHARYL ATTKISSON Updated Aug. 6 with CDC analysis of Kentucky (unvaccinated Kentuckians had “2.34 times the odds of reinfection“ compared with fully vaccinated) and national analysis in […]
Adaptive immune responses to SARS-CoV-2 infection in severe versus mild individuals
Authors: Fan Zhang, Rui Gan, Ziqi Zhen, Xiaoli Hu, Xiang Li, Fengxia Zhou, Ying Liu, Chuangeng Chen, Shuangyu Xie, Bailing Zhang, Xiaoke Wu & Zhiwei Huang Signal Transduction and Targeted Therapy volume 5, Article number: 156 (2020) Abstract The global Coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 […]
Adaptive immunity to SARS-CoV-2 and COVID-19
Authors: Alessandro Sette1,2 and Shane Crotty1,2,∗ Abstract The adaptive immune system is important for control of most viral infections. The three fundamental components of the adaptive immune system are B cells (the […]
Adaptive immunity to SARS-CoV-2 and COVID-19
Authors: Alessandro Sette 1, Shane Crotty 2 Abstract The adaptive immune system is important for control of most viral infections. The three fundamental components of the adaptive immune system are B cells (the […]