Abstract Transverse myelitis (TM) is an inflammatory disorder of the spinal cord characterized by acute or subacute development of bilateral motor, sensory, and autonomic dysfunction attributable to focal spinal cord […]
Long COVID and Autonomic Nervous System Dysfunction
John Murphy, CEO The COVID-19 Long-haul Foundation Abstract Post-acute sequelae of SARS-CoV-2 infection (PASC), commonly termed Long COVID, represents a multisystem disorder characterized by persistent, relapsing, or new-onset symptoms extending […]
Progressive Neuropathy in Long COVID: Etiology, Pathogenesis, Genomics, Clinical Evolution, Therapeutic Strategies, and Vaccine Implications
Abstract Post-acute sequelae of SARS-CoV-2 infection (PASC), commonly termed Long COVID, represents one of the largest emerging chronic disease burdens of the twenty-first century. Although pulmonary and cardiovascular manifestations initially […]
Peripheral Sensory Dysfunction in Long COVID: Etiology, Genomics, Pathophysiology, Clinical Manifestations, Diagnostic Approaches, Disease Progression, and Long-Term Outcomes
John Murphy, MD., M.P.H., D.P.H., CEO, COVID-19 long-haul Foundation Abstract Long COVID, also known as Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), has emerged as one of the most significant chronic […]
COVID-19 and Loss of Sensory-motor Function
John Murphy, CEO Covid 10 Long-haul Foundationn Loss of sensory-motor function affecting the hands, arms, legs, and feet has become one of the more disabling neurological manifestations reported after acute […]
COVID-19 and the Motor–Sensory Brain: Pathobiology, Microvascular Injury, Neurophysiology, Clinical Manifestations, Therapeutic Strategies, and Long-Term Outcomes
John Murphy, CEO COVID-19 Long-haul Founndation Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), initially characterized as a respiratory pathogen, is now recognized as a systemic vascular and neurotropic disease […]
NIH RECOVER Clinical Trials and the First Emergence of Interventional Results in Long COVID Research: A Translational Turning Point
A Scholarly Review for Scientific American (Submission-Style Manuscript) John Murphy, M.D., M.P.H., D.P.H., President, COVID-19 Long-Haul Foundation Abstract The NIH RECOVER Initiative represents the largest coordinated research program investigating post–acute […]
Persistent Viral Reservoirs and Immune Dysregulation in Long COVID
John Murphy, M.D., M.P.H., D.P.H., President Covid-19 Long-haul Foundation The Central Discovery Reshaping Post-Acute Sequelae Research Abstract Long COVID (post-acute sequelae of SARS-CoV-2 infection, PASC) has emerged as a multisystem […]
COVID-19–Associated Neuropathy of the Feet and Legs: Etiology, Pathophysiology, Clinical Course, and Therapeutic Approaches
Abstract Peripheral neuropathy involving the feet and legs has emerged as one of the most prevalent and disabling neurological sequelae associated with acute and post-acute COVID-19 illness. Although initially overshadowed […]
COVID-19 and Motor Nerve Involvement: A Neurological Perspective on Post-Viral Neuropathy
John Murphy, CEO The COVID-19 Long-haul Foundation Introduction The emergence of SARS-CoV-2 in late 2019 marked the beginning of a global health crisis that has since reshaped the landscape of […]