Category: Autoimmune Disease

COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedside

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David Sulzer, Angelo Antonini, Valentina Leta, Anna Nordvig, Richard J. Smeyne, James E. Goldman, Osama Al-Dalahmah, Luigi Zecca, Alessandro Sette, Luigi Bubacco, Olimpia Meucci, Elena Moro, Ashley S. Harms, Yaqian Xu, Stanley Fahn & K. Ray Chaudhuri  npj Parkinson’s Disease volume 6, Article number: 18 (2020) Cite this article Abstract This Viewpoint discusses insights from basic science and clinical perspectives on coronavirus disease 2019 (COVID-19)/severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection in the brain, with a particular focus […]

COVID-19 can trigger auto-immune disorders-related antibodies, causing thrombosis and other complications

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SEPTEMBER 12, 2023 by Maria Fernanda Ziegler, FAPESP Medical Express An article published in npj Aging reveals that natural production of auto-antibodies increases with age, and that infection by SARS-CoV-2 can exacerbate production of auto-antibodies relating to auto-immune diseases, helping to explain why aging increases the chances of developing severe COVID-19. The study also discovered some of the factors that […]

Detrimental effects of COVID-19 in the brain and therapeutic options for long COVID: The role of Epstein–Barr virus and the gut–brain axis

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Kenji Hashimoto, Molecular Psychiatry (2023) Published: 04 July 2023 Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public health burden worldwide. In addition to respiratory, heart, and gastrointestinal symptoms, patients infected with SARS-CoV-2 experience a number of persistent neurological and psychiatric symptoms, known as […]

What you need to know about Covid as new variant rises

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September 24, 2023 BBC News Jim Reed The number of people in hospital has gone up. Google searches have doubled in a month and booster vaccines have been brought forward because of a new variant. It might all feel a bit 2021. But – these days – how much do we really need to worry […]

Microvascular Injury in the Brains of Patients with Covid-19

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February 4, 2021 N Engl J Med 2021; 384:481-483 DOI: 10.1056/NEJMc2033369 304 Citing Articles TO THE EDITOR: We conducted postmortem high-resolution magnetic resonance imaging (magnetic resonance microscopy) of the brains of patients with coronavirus disease 2019 (Covid-19) (median age, 50 years) and histopathological examination that focused on microvascular changes in the olfactory bulb and brain stem. […]

Key biological pathway reveals insights into long COVID brain fog

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by Lilly Matson, University of New South Wales AUGUST 16, 2023 Medical Express Researchers from University of New South Wales Sydney and St. Vincent’s Hospital have identified a key pathway, involved in inflammation, which appears to be activated in people with long COVID who have symptoms of “brain fog.” Scientists from the School of Psychology and […]

Researchers find immune response to COVID strengthens over time

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by Erik Robinson, Oregon Health & Science University JANUARY 25, 2023 Immunity from COVID-19 appears to gather strength with more time between vaccination and infection, a new laboratory study from researchers at Oregon Health & Science University suggests. The findings carry implications for vaccine recommendations as the pandemic transitions to an endemic state. Researchers measured the […]

Post-COVID Interstitial Lung Disease—The Tip of the Iceberg

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Namrata Kewalramani, MD,a,b,∗ Kerri-Marie Heenan, MB Bch, BAO,c Denise McKeegan, MB Bch, BAO, MSc,c and Nazia Chaudhuri, MD, PhDd Immunol Allergy Clin North Am. 2023 May; 43(2): 389–410. Published online 2023 Mar3. doi: 10.1016/j.iac.2023.01.004 PMCID: PMC9982726PMID: 37055095 The proportion of symptomatic patients with post-coronavirus 2019 (COVID-19) condition (long COVID) represents a significant burden on the individual as well as on the health care systems. […]

‘Spikeopathy’: COVID-19 Spike Protein Is Pathogenic, from Both Virus and Vaccine mRNA

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Peter I. Parry, Astrid Lefringhausen, Conny Turni, Christopher J. NeilRobyn Cosford, Nicholas J. Hudson  and, Julian Gillespie Children’s Health Research Clinical Unit, Faculty of Medicine, The University of Queensland, Biomedicines 2023, 11(8), 2287; https://doi.org/10.3390/biomedicines11082287 Received: 17 June 2023 / Revised: 17 July 2023 / Accepted: 24 July 2023 / Published: 17 August 2023 Abstract The COVID-19 pandemic caused much illness, many deaths, and profound […]

Cutting Edge: Circulating Exosomes with COVID Spike Protein Are Induced by BNT162b2 (Pfizer–BioNTech) Vaccination prior to Development of Antibodies: A Novel Mechanism for Immune Activation by mRNA Vaccines 

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Sandhya Bansal, Sudhir Perincheri, Timothy Fleming,Christin Poulson, Brian Tiffany, Ross M. Bremner;Thalachallour Mohanakumar Author & Article Information J Immunol (2021) 207 (10): 2405–2410. https://doi.org/10.4049/jimmunol.2100637 Abstract Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) causes severe acute respiratory syndrome. mRNA vaccines directed at the SARS-CoV-2 spike protein resulted in development of Abs and protective immunity. To determine the mechanism, we analyzed […]