John Murphy, CEO The COVID-19 Long haul Foundation: Original Research Study An Integrated Analysis of Government, Public, Electronic Health-Record, Genomic, and Published Clinical Databases, 2020–2025 Abstract Background: COVID-19 is frequently […]
Toward a Blood-Based Diagnostic Test for Long COVID
An Evidence Synthesis and Framework for a Multimarker Diagnostic Signature John Murphy, M.D., M.P.H., D.P.H., COVID-19 Long-haul Foundation Abstract Objective To determine whether currently available clinical, immunological, proteomic, metabolomic, vascular […]
SARS-CoV-2 and the Laboratory Hypothesis: A Scientific Examination of the Evidence
John Murphy, M.D., M.P.H., D.P.H., COVID-19 Long-haul Foundation Summary The origin of SARS-CoV-2 remains one of the most consequential unresolved questions in modern infectious-disease science. The central issue is not […]
Vaccinated Long COVID May Be a Different Disease
How vaccination may alter the biological architecture—not merely the probability—of post-COVID illness John Murphy, M.D., M.P.H., D.P.H., CEO, The COVID-19 Long-haul Foundation Abstract The dominant question surrounding COVID-19 vaccination and […]
Cancer After COVID-19 Vaccination: Separating a Safety Signal From a Causal Claim
What population-scale data can—and cannot—tell us about an increasingly consequential hypothesis John Murphy, M.D., M.P.H., D.P.H., The COVID-19 Long-haul Foundation Summary The possibility that COVID-19 vaccination might influence cancer incidence […]
Why Do Some People Recover from SARS-CoV-2 Infection While Others Develop Long COVID?
A Multidimensional Analysis of Predictors of Persistent Disease John Murphy, M.D., M.P.H., D.P.H., COVID-19 Long-haul Foundation Abstract ObjectiveTo determine which clinical, demographic, immunological, virological and treatment-related factors are associated with […]
The Disease After the Disease: Measuring the Long-Term Excess Burden of New Chronic Illness Following SARS-CoV-2 Infection
John Murphy, M.D., M.P.H., D.P.H., CEO, The COVID-19 Long-haul Foundation Abstract More than six years after the emergence of SARS-CoV-2, an important question remains incompletely answered: Does COVID-19 merely produce […]
Long-term organ-system consequences of SARS-CoV-2 infection
A cross-dataset analysis of persistent health loss, disability, and multisystem sequelae John Murphy, CEO, The COVID-19 Long-haul Foundation Manuscript type: Analysis / evidence synthesis Data source note: This manuscript is […]
Long COVID Is Not One Disease
What millions of medical records reveal about the hidden phenotypes of a disease that can follow SARS-CoV-2 infection John Murphy, CEO, The COVID-19 Long Haul Foundation Abstract Long COVID is […]
Long COVID and Analysis of Recovery, Persistence and Worsening Illnesses
John Murphy, CEO, The COVID-19 Long-haul Foundation Abstract Long COVID is increasingly recognized not as a uniform post-infectious syndrome but as a heterogeneous disease whose manifestations evolve over time. Yet […]