Six years after SARS-CoV-2 emerged, researchers are no longer asking whether patients are sick. They are trying to understand why the same infection can leave one person with debilitating fatigue, […]
Autonomic Dysfunction as a Major Phenotype of Long COVID
Etiology, pathology, genomics, physiology, and clinical course of post-SARS-CoV-2 autonomic disease John Murphy, CEO, The COVID-19 Long haul Foundation Abstract Autonomic dysfunction has emerged as one of the most reproducible […]
The Epidermal Footprint of Long COVID
John Murphy, CEO, The COVID-19 Long haul Foundation A narrative review Abstract BackgroundPost-COVID-19 condition, commonly termed long COVID, is a multisystem disorder in which symptoms persist, recur, or newly develop […]
Viral Reactivation and Long COVID: The Emerging Biology of SARS-CoV-2
Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), has evolved from an initially enigmatic constellation of persistent symptoms into a biologically heterogeneous syndrome characterized by abnormalities involving immunity, […]
Evidence for Persistent Viral Material in Long COVID
John Murphy, CEO, COVID-19 Long-Haul Foundation Abstract Importance More than six years after the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), post-acute sequelae of COVID-19 (PASC), commonly known […]
Autoimmunity and Long COVID
Abstract Background. Long COVID, also termed post-COVID-19 condition or post-acute sequelae of SARS-CoV-2 infection (PASC), is a heterogeneous multisystem disorder that may follow mild or severe acute infection. Increasing evidence […]
China COVID-19 Surge: Cases in Jump Over 560%
BEIJING – China is currently facing a massive new wave of COVID-19 infections this summer. Health officials are watching the numbers closely as cases skyrocket across the entire country. Hospitals are […]
COVID-19 and Dysautonomia: From Vagal Injury to Systemic Physiological Failure
A narrative review of autonomic dysfunction, vagal disruption, pathophysiology and clinical course in Long COVID Abstract Background: Dysautonomia has emerged as one of the most consequential neurological and cardiovascular manifestations […]
When the Virus Leaves, but the Darkness Remains
COVID-19, Long COVID, and the Biology of Persistent Depression John Murphy, CEO The COVID-19 Long haul Foundation Introduction: A Depression That May Not Begin in the Mind Among the many […]
Mitochondrial and Metabolic Dysfunction in Long COVID: A Bioenergetic Model of Fatigue, Post-Exertional Malaise, and Multisystem Disease
Etiology, pathology, genomics, physiology, and clinical course Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is a heterogeneous multisystem disorder in which fatigue, post-exertional malaise, cognitive dysfunction, autonomic […]