Background John Murphy, CEO COV-19 Long-haul Foundation Persistent dermatologic manifestations represent an increasingly recognized component of post-acute sequelae of SARS-CoV-2 infection (PASC), commonly termed Long COVID. Among these manifestations, chronic […]
Long COVID and Chronic Diffuse Pruritus
John Murphy, MD., M.P.H., D.P.H., President COVID Long-haul Foundation Abstract Long COVID, also termed post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as one of the defining chronic illnesses of […]
COVID-19 and Hair Follicle Biology
A Comprehensive Review of Etiology, Physiology, Pathology, Proteomics, and Therapeutic Approaches 1. Abstract COVID-19, caused by SARS-CoV-2, is associated with a broad spectrum of post-infectious dermatologic sequelae, most prominently diffuse […]
Skin Defects & Long COVID: Etiology, Pathophysiology, Clinical Progression, and Therapeutic Strategies
Abstract John Murphy, M.D., M.P.H., D.P.H., President The Covid-19 Long-haul Foundation Long COVID, also termed post-acute sequelae of SARS-CoV-2 infection (PASC), has emerged as a chronic multisystem disorder affecting millions […]
SARS-CoV-2 Infection of Human Epithelial Tissues
John Murphy, CEO The COVID-19 Long-haul Foundation Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of coronavirus disease 2019 (COVID-19), is a pleiotropic pathogen with profound effects […]
🧬 The Endothelium as a Viral Interface
John Murphy, CEO The COVID-19 Long-haul Foundation The endothelium, a monolayer of cells lining the interior of blood vessels, is often regarded as a passive conduit for blood flow. Yet […]
SARS-CoV-2–Associated Injury to Human Epithelial Tissues
Authors: John Murphy, M.D., MPH, DPH. ,Affiliations: President COVID-19 Long-haul FoundationAbstract: 250 words Abstract BackgroundSARS-CoV-2 infection produces multisystem disease with prominent epithelial involvement extending beyond the respiratory tract. Increasing evidence […]
Etiology of Long COVID Skin Conditions
John Murphy, CEO, The COVID-19 Long-haul Foundation Introduction The COVID‑19 pandemic has left an indelible mark not only on global health systems but also on the human body in ways […]
Heightened Innate Immune and Inflammatory Gene Expression in the Skin of Severe COVID-19 Cases
Authors Fernandes IG, Ferreira FM, De Sousa ESA , Pet.al., DOI https://doi.org/10.2147/JIR.S516737 Correspondence: Maria Notomi Sato, Laboratory of Medical Investigation in Dermatology and Immunodeficiencies (LIM-56), Department of Dermatology, Faculdade de Medicina, Universidade de Sao Paulo, Sao […]
Persistent Inflammation and Cutaneous Dysregulation: Long COVID & Urticaria
Author: John Murphy Affiliation: COVID-19 Long-haul Foundation Introduction The COVID-19 pandemic has left a legacy far beyond acute respiratory illness. For millions worldwide, recovery from SARS-CoV-2 infection has been followed […]