SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids


Authors: Laura Pellegrini 1, Anna Albecka 1, Donna L Mallery 1, Max J Kellner 1, David Paul 1, Andrew P Carter 1, Leo C James 1, Madeline A Lancaster 2 Abstract Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…[...]

NIH study uncovers blood vessel damage and inflammation in COVID-19 patients’ brains but no infection


Authors: Christopher G. Thomas, 301-496-5751, nindspressteam@ninds.nih.gov Results from a study of 19 deceased patients suggests brain damage is a byproduct of a patient’s illness. In an in-depth study of how COVID-19…[...]

COVID and the brain: researchers zero in on how damage occurs


Authors: Michael Marshall Growing evidence suggests that the coronavirus causes ‘brain fog’ and other neurological symptoms through multiple mechanisms. How COVID-19 damages the brain is becoming clearer. New evidence suggests…[...]

COVID-19 is, in the end, an endothelial disease


Authors: Peter Libby, Thomas Lüscher The vascular endothelium provides the crucial interface between the blood compartment and tissues, and displays a series of remarkable properties that normally maintain homeostasis. This tightly…[...]

Endothelial dysfunction contributes to COVID-19-associated vascular inflammation and coagulopathy


Authors: Jun Zhang 1, Kristen M Tecson 1, Peter A McCullough 1 2 3 Great attention has been paid to endothelial dysfunction (ED) in coronavirus disease 2019 (COVID-19). There is growing evidence to suggest that the angiotensin…[...]