Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

Suo-wen Xu, Iqra Ilyas & Jian-ping Weng  Acta Pharmacologica Sinica volume 44, pages695–709 (2023) Cite this article 17 October 2022 Abstract The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is still raging. However,…[...]

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COVID-19 can trigger auto-immune disorders-related antibodies, causing thrombosis and other complications

SEPTEMBER 12, 2023 by Maria Fernanda Ziegler, FAPESP Medical Express The systems immunology approach identifies an aging effect on autoantibody levels of COVID-19 patients. Credit: npj Aging (2023). DOI: 10.1038/s41514-023-00118-0 An article published in npj Aging reveals…[...]

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Detrimental effects of COVID-19 in the brain and therapeutic options for long COVID: The role of Epstein–Barr virus and the gut–brain axis

Kenji Hashimoto, Molecular Psychiatry (2023) Published: 04 July 2023 Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public health…[...]

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Doxycycline, a widely used antibiotic in dermatology with a possible anti‐inflammatory action against IL‐6 in COVID‐19 outbreak

Claudio Conforti, 1 Roberta Giuffrida, 2 Iris Zalaudek, 1 and Nicola Di Meo 1 Dermatol Ther. 2020 Jul-Aug; 33(4): e13437. Published online 2020 May 15. doi: 10.1111/dth.13437 PMCID: PMC7235480PMID: 32314492 The recent SARS‐CoV‐2 pandemic, for which there is still no approved vaccine, required…[...]

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Multi-layered transcriptomic analyses reveal an immunological overlap between COVID-19 and hemophagocytic lymphohistiocytosis associated with disease severity

Authors: Lena F. Schimkea,5, Alexandre H.C. Marquesa, Gabriela Crispim Baiocchia, Caroline Aliane de Souza Pradob Dennyson Leandro M. Fonsecab , Paula Paccielli Freirea , Desirée Rodrigues Plaçab , Igor Salerno…[...]

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