🔬 Overview As the COVID-19 pandemic enters its fifth year, dermatological manifestations remain a key area of clinical and immunological inquiry. Among these, chilblains—also known as pernio—have emerged as a […]
🩸 COVID-19 and Chronic Venous Insufficiency: 2025 Research Insights on Etiology, Vascular Damage, and Treatment
Chronic Venous Insufficiency (CVI)—a condition where leg veins fail to return blood efficiently to the heart—has gained renewed attention in 2025 due to its association with COVID-19, particularly in patients […]
Intranasal Chlorpheniramine for Early Symptomatic Treatment of COVID-19 and the Impact on Long-COVID
Gustavo Ferrer • Fernando Valerio-Pascua • CĂ©sar Alas-Pineda • et.al., DOI: 10.7759/cureus.82736 Abstract This review explores the therapeutic potential of intranasal chlorpheniramine maleate (iCPM) in managing both acute COVID-19 and Long COVID by integrating histamine H1 receptor […]
CD56+Â Monocytes and CD31+Â Endothelial Cells Are Increased in Severe COVID-19 DiseaseÂ
Abstract Immune response dysregulation plays a key role in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis. In this study, we evaluated immune and endothelial blood cell profiles of patients […]
A Systematic Review of Case Reports of New-Onset Atrial Fibrillation in COVID-19 Patients
Rocio Barriga Guzman • Oluwaremilekun Tolu-Akinnawo • Toluwalase Awoyemi • et. al DOI: 10.7759/cureus.78938 Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic posed a significant global public health challenge, affecting millions of individuals. While some […]
How COVID-19 Affects the Brain
Maura Boldrini, MD, PhD1,2; Peter D. Canoll, MD, PhD3; Robyn S. Klein, MD, PhD4,5,6, JAMA Psychiatry. 2021;78(6):682-683. doi:10.1001/jamapsychiatry.2021.0500 COVID-19 has resulted in more than 120 million cases and 2.6 million deaths to date. Respiratory and gastrointestinal symptoms are accompanied […]
Long Covid: Hormone Imbalances and/or Rather Complex Immune Dysregulations?Â
Christian A Koch, Journal of the Endocrine Society, Volume 8, Issue 5, May 2024, bvae043, https://doi.org/10.1210/jendso/bvae043 Approximately 5% of all individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) do […]
Long Covid explanation in new study possibly paves way for tests and treatments
By Barbara Mantel, NBC News Scientists say that drugs that calm a key part of the immune system should be studied in clinical trials as potential long Covid treatments. Scientists have […]
Severe Coronary Vasospasms in Asymptomatic COVID-19
Omar M. Masarweh • Ubaldo Gonzalez-Morales • Sara Tahir • Sana Tahir • Sayed T. Hussain, 2024, DOI: 10.7759/cureus.64869 Abstract Since the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019, we have witnessed its multi-organ […]
A Unique Case of Unprovoked Pulmonary Venous Thrombosis in a Postpartum Female Following COVID-19 Infection
Jordan Lipschutz • Sophia H. Ji • Mohammad Q. Jafri • Ambica Nair • Brian Kerr, 2024, DOI: 10.7759/cureus.64893 Abstract SARS-CoV-2 can induce a hypercoagulable state, occasionally resulting in pulmonary venous thrombosis (PVT) due to inflammation and endothelial injury. […]