SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids


Authors: Laura Pellegrini 1, Anna Albecka 1, Donna L Mallery 1, Max J Kellner 1, David Paul 1, Andrew P Carter 1, Leo C James 1, Madeline A Lancaster 2 Abstract Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, leads to respiratory symptoms that can be fatal. However, neurological symptoms have also been observed in some patients. The cause of these complications is […]

NIH study uncovers blood vessel damage and inflammation in COVID-19 patients’ brains but no infection


Authors: Christopher G. Thomas, 301-496-5751, nindspressteam@ninds.nih.gov Results from a study of 19 deceased patients suggests brain damage is a byproduct of a patient’s illness. In an in-depth study of how COVID-19 affects a patient’s brain, National Institutes of Health researchers consistently spotted hallmarks of damage caused by thinning and leaky brain blood vessels in tissue samples […]

COVID and the brain: researchers zero in on how damage occurs


Authors: Michael Marshall Growing evidence suggests that the coronavirus causes ‘brain fog’ and other neurological symptoms through multiple mechanisms. How COVID-19 damages the brain is becoming clearer. New evidence suggests that the coronavirus’s assault on the brain could be multipronged: it might attack certain brain cells directly, reduce blood flow to brain tissue or trigger […]

COVID Vaccines May Bring Avalanche of Neurological Disease


Authors: Dr. Mercola Interviews the Experts Any medical treatment must be evaluated along a cost-benefit analysis. No treatment is risk free. It is in this respect that transparent availability of risk-group-stratified data on potential effects of vaccination, as compared to corresponding unvaccinated groups, must be available. These should be analysed by specialists free of any […]

Clots, Strokes and Rashes: Is COVID a Disease of the Blood Vessels?


Authors: Will Stone Whether it’s strange rashes on the toes or blood clots in the brain, the widespread ravages of COVID-19 have increasingly led researchers to focus on how the novel coronavirus sabotages blood vessels. As scientists have come to know the disease better, they have homed in on the vascular system — the body’s […]

COVID-19 is, in the end, an endothelial disease


Authors: Peter Libby, Thomas Lüscher The vascular endothelium provides the crucial interface between the blood compartment and tissues, and displays a series of remarkable properties that normally maintain homeostasis. This tightly regulated palette of functions includes control of haemostasis, fibrinolysis, vasomotion, inflammation, oxidative stress, vascular permeability, and structure. While these functions participate in the moment-to-moment regulation […]

Endothelial dysfunction contributes to COVID-19-associated vascular inflammation and coagulopathy


Authors: Jun Zhang 1, Kristen M Tecson 1, Peter A McCullough 1 2 3 Great attention has been paid to endothelial dysfunction (ED) in coronavirus disease 2019 (COVID-19). There is growing evidence to suggest that the angiotensin converting enzyme 2 receptor (ACE2 receptor) is expressed on endothelial cells (ECs) in the lung, heart, kidney, and intestine, particularly in systemic vessels (small and […]