The Specter of Endothelial Injury in COVID-19


Studies signal that damage to the endothelium—cells that cover blood vessels like wallpaper—could underpin the thrombosis and inflammation induced by coronavirus infection. The endothelium as a common theme in COVID-19 The endothelium comprises a single layer of cells that forms the interior lining of blood vessels throughout the body. The tissue physically insulates blood elements […]

COVID-19: towards understanding of pathogenesis


Since the end of 2019, COVID-19 has caused considerable mortality and morbidity worldwide, and become a priority of the global society. Better understanding the pathogenesis of COVID-19 will provide important insight into its management. The pandemic of coronavirus disease 2019 (COVID-19) is spreading rapidly. Although the cause was quickly identified as a new coronavirus named […]

Spike Proteins, COVID-19, and Vaccines


A recent study looks at the effects of the SARS-CoV-2 spike proteins, showing that they can cause some of the harm of COVID-19 by themselves. This is an important advance in our understanding of the disease and hopefully will lead to new therapeutic interventions. The spike protein is what gives the coronavirus family of viruses their […]

Simplifying Covid-19 Into One Mechanism: The Epithelial-endothelial Crosstalk


The Multifaceted Covid-19 We see all imaginable symptoms with Covid-19, which is supposed to be a pneumonia disease. Yet Covid-19 can affect the brain, peripheral nerves, olfaction, taste, throat, thyroid, liver, gastrointestinal tract, kidneys, spleen, semen, skin, blood vessels, toes, and probably more to come. It’s intriguing how one virus, SARS-CoV-2, could cause so many symptoms. Is there actually a unifying mechanism of disease progression that could explain most […]

COVID-19 Autopsies Put Endothelial Damage, Angiogenesis in the Spotlight


More autopsy reports on COVID-19 patients, some from the United States, are helping researchers piece together a picture of a virus that damages endothelial cells, causing a clotting disorder that can lead to deep vein thrombosis and pulmonary emboli. “These people are in a hypercoagulant state, and early anticoagulation is important,” said Louis Maximilian Buja, […]

Clots, Strokes and Rashes: Is COVID a Disease of the Blood Vessels?


Whether it’s strange rashes on the toes or blood clots in the brain, the widespread ravages of COVID-19 have increasingly led researchers to focus on how the novel coronavirus sabotages blood vessels. As scientists have come to know the disease better, they have homed in on the vascular system — the body’s network of arteries, […]

WHO changes definition of herd immunity


In a June 14, 2021 article by Christianity Daily, Dr. Marty Makary of John’s Hopkins School of Medicine is quoted as saying the the US has achieved herd immunity for the Covid virus. About 50% of the US population have had the corona virus and about 132 million Americans have been fully vaccinated. He estimates […]

Why is no one talking about immunity in people who have had corona virus?


The fully vaccinated have finally been given a “get out of jail free card” from the CDC, while those who suffered through the covid infection remain personae non gratae. The National Institutes of Health published a study on June 18, 2020 of the evidence of protective antibodies in those who have been infected with covid. […]

To Mask or Not to Mask, That is the Question?


As more people are vaccinated and summer weather brings us out of doors, the social distancing and masking debate continues. Many states are loosening restrictions and most schools finally opened for in person learning in the late spring. In Atlanta, you can see people in restaurants and stores maskless! CDC’s Dr. Fauci recently told viewers […]