Runaway immune reactions cause long COVID breathing problems

Author: Christopher Vaughan, Stanford Medicine 2023 Stanford Medicine researchers have found a mechanism behind one of the most common symptoms of long COVID — shortness of breath. Post COVID-19 breathing problems are caused by a condition known as lung fibrosis, when damaged lungs form scar tissue, which makes it difficult for lungs to expand and […]

Molecular mechanisms of COVID-19-induced pulmonary fibrosis and epithelial-mesenchymal transition

Authors: Peng Pi1† Zhipeng Zeng1† Liqing Zeng1 Bing Han1 Xizhe Bai2 Shousheng Xu3*Front. Pharmacol., 03 August 2023, Sec. Respiratory Pharmacology, Volume 14 – 2023 | As the outbreak of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first broke out in Hubei Province, China, at the end of 2019. It has brought great challenges and harms to global […]

Spectrum of Fibrotic Lung Diseases

Marlies Wijsenbeek, M.D., and Vincent Cottin, M.D.  New England Journal of Medicine 2023 Diffuse parenchymal lung diseases encompass a large number of conditions, with a wide range of causes, clinical manifestations, and imaging and pathological features, as well as variable outcomes. Despite the intrinsic heterogeneity of this group of diseases, in most of them, the […]

Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID)

Jim M Wild1, Joanna C Porter2,3,4, Philip L Molyneaux5,6, Peter M George5,6, Stewart5, Richard James Allen7, Raminder Aul8, Kenneth Baillie9, Shaney L Barratt10, Paul Beirne11, Stephen M Bianchi12, John F Blaikley13,14, Jonathan Brooke15,16,17, Chaudhuri14,18, Guilhem Collier1, K Denneny2,3,4, Annemarie Docherty19, Fabbri5, Michael A Gibbons20,21, Fergus V Gleeson22, Bibek Gooptu23,24, Ian P Hall16,17, Neil A Hanley14,25, Melissa Heightman3, Toby E Hillman3, R Johnson16,17, Mark G Jones26,27, Khan16,17, Rod Lawson12, Puja Mehta2,28, Jane A Mitchell5, Platé2,29, Krisnah Poinasamy30, Jennifer K Quint5, Pilar […]

Post-COVID Interstitial Lung Disease: What you Need to Know

Pulmonary Fibrosis Foundation, Apr 28, 2023 After being hospitalized for three months with COVID-19 and double pneumonia in 2020, Houston police officer Hito Bazan awoke one morning to discover that he couldn’t talk, eat, walk, or most importantly, breathe. Bazan was diagnosed with interstitial lung disease (ILD) known as pulmonary fibrosis (PF). Three years into […]

Interstitial Lung Disease after COVID-19 Infection: A Catalog of Uncertainties

Athol U. Wells, Anand Devaraj, Sujal R. Desai Jan 26 2021 Coronavirus disease 2019 (COVID-19) has now caused more than a million deaths worldwide. These deaths are often due to severe pulmonary involvement. In fatal cases, features of diffuse alveolar damage are a frequent finding. Many survivors with severe infection have long-term residual abnormalities on their thoracic […]

1000 Peer Reviewed Studies Questioning Covid-19 Vaccine Safety

Peer Reviewed Medical Papers Submitted To Various Medical Journals, Evidencing A Multitude Of Adverse Events In Covid-19 Vaccine Recipients. The list includes studies published as of January 20, 2022 concerning the potential adverse reaction from COVID-19 vaccines, such as myocarditis, thrombosis, thrombocytopenia, vasculitis, cardiac, Bell’s Palsy, immune-mediated disease, and many more. Myocarditis after mRNA vaccination […]

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

Authors.Maximilian Ackermann, M.D., Stijn E. Verleden, Ph.D., Mark Kuehnel, Ph.D., Axel Haverich, M.D., Tobias Welte, M.D., Florian Laenger, M.D., Arno Vanstapel, Ph.D., Christopher Werlein, M.D., Helge Stark, Ph.D., Alexandar Tzankov, M.D., William W. Li, M.D., Vincent W. Li, M.D., et al. July 9, 2020 N Engl J Med 2020; 383:120-128 DOI: 10.1056/NEJMoa2015432 Abstract BACKGROUND Progressive respiratory failure is the primary cause of death in the coronavirus disease […]

The characteristics and evolution of pulmonary fibrosis in COVID-19 patients as assessed by AI-assisted chest HRCT

Authors: Jia-Ni Zou , Liu Sun , Bin-Ru Wang , You Zou , Shan Xu, Yong-Jun Ding, Li-Jun Shen, Wen-Cai Huang, Xiao-Jing Jiang, Shi-Ming Chen  Published: March 23, 2021 Abstract The characteristics and evolution of pulmonary fibrosis in patients with coronavirus disease 2019 (COVID-19) have not been adequately studied. AI-assisted chest high-resolution computed tomography (HRCT) was used to […]