Authors: DATED: AUGUST 6, 2021 BY SHARYL ATTKISSON Updated Aug. 6 with CDC analysis of Kentucky (unvaccinated Kentuckians had “2.34 times the odds of reinfection“ compared with fully vaccinated) and national analysis in Israel (vaccinated Israelis were 6.72 times more likely to get infected after the shot than after natural infection). More below. Sen. Lindsey Graham (R-S.C.) became […]
Authors: Fan Zhang, Rui Gan, Ziqi Zhen, Xiaoli Hu, Xiang Li, Fengxia Zhou, Ying Liu, Chuangeng Chen, Shuangyu Xie, Bailing Zhang, Xiaoke Wu & Zhiwei Huang Signal Transduction and Targeted Therapy volume 5, Article number: 156 (2020) Abstract The global Coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has affected more than eight million people. There is an urgent need to investigate how the adaptive immunity is established in COVID-19 patients. In this […]
Authors: Alessandro Sette1,2 and Shane Crotty1,2,∗ Abstract The adaptive immune system is important for control of most viral infections. The three fundamental components of the adaptive immune system are B cells (the source of antibodies), CD4+ T cells, and CD8+ T cells. The armamentarium of B cells, CD4+ T cells, and CD8+ T cells has differing roles in different viral infections and in vaccines, and […]
Authors: Alessandro Sette 1, Shane Crotty 2 Abstract The adaptive immune system is important for control of most viral infections. The three fundamental components of the adaptive immune system are B cells (the source of antibodies), CD4+ T cells, and CD8+ T cells. The armamentarium of B cells, CD4+ T cells, and CD8+ T cells has differing roles in different viral infections […]
Authors: Natalia T Freund, Motti Gerlic, Ben A Croker The end of the coronavirus disease 2019 (COVID-19) pandemic is in sight. We have scientists to thank for that. However, while years of meticulous research by vaccinologists, molecular biologists and immunologists provided the framework for rapid deployment of vaccines, we are still learning what constitutes an effective lifelong […]
Authors: Rebecca J. Cox & Karl A. Brokstad Nature Reviews Immunology volume 20, pages581–582 (2020) Recent reports that antibodies to SARS-CoV-2 are not maintained in the serum following recovery from the virus have caused alarm. However, the absence of specific antibodies in the serum does not necessarily mean an absence of immune memory. Here, we discuss our current understanding of the […]
Authors: By Dr. Liji Thomas, MD The disease course of COVID-19 is diverse, ranging from asymptomatic to fatal respiratory failure. Emory University scientists have been working to uncover the immunological reasons behind this heterogeneity. A recent study on B cells, published on the preprint server medRxiv* in April 2020, shows that extrafollicular B cells could be a marker […]
Authors: Gemma E Hartley 1, Emily S J Edwards 1, Pei M Aui 1, Nirupama Varese 1 2, Stephanie Stojanovic 3, James McMahon 4 5, Anton Y Peleg 4 6, Irene Boo 7, Heidi E Drummer 7 8 9, P Mark Hogarth 1 10 11, Robyn E O’Hehir 1 2 3, Menno C van Zelm 12 2 Abstract Lasting immunity following SARS-CoV-2 infection is questioned because serum antibodies decline in convalescence. However, functional immunity is mediated by long-lived memory T and B (Bmem) cells. Therefore, we generated fluorescently-labeled […]
Authors: Beth Daley, Editor and General Manager To get the upper hand on the coronavirus, we first need to understand how our immune system reacts to it. Understanding this will lead to better treatments, effective vaccines and knowing how near we are to herd immunity – and if it’s even achievable. Every day, new research […]
Authors: References: Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection. Dan JM, Mateus J, Kato Y, Hastie KM, Yu ED, Faliti CE, Grifoni A, Ramirez SI, Haupt S, Frazier A, Nakao C, Rayaprolu V, Rawlings SA, Peters B, Krammer F, Simon V, Saphire EO, Smith DM, Weiskopf D, Sette A, Crotty S. Science. 2021 […]
