Human SARS-CoV-2 challenge uncovers local and systemic response dynamics

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Rik G. H. Lindeboom, Kaylee B. Worlock, Lisa M. Dratva, et. al.Nature (2024) Abstract The COVID-19 pandemic is an ongoing global health threat, yet our understanding of the dynamics of early cellular responses to this disease remains limited1. Here in our SARS-CoV-2 human challenge study, we used single-cell multi-omics profiling of nasopharyngeal swabs and blood to temporally resolve abortive, […]

Safety and efficacy of low dose naltrexone in a long covid cohort; an interventional pre-post study.

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O’Kelly B 1,2, Vidal L 2, McHugh T 2, et. al. Brain, Behavior, & Immunity – Health, 03 Jul 2022, 24:100485, https://doi.org/10.1016/j.bbih.2022.100485 PMID: 35814187 PMCID: PMC9250701 Abstract  Background Up to 37.7% of patients experience symptoms beyond 12 weeks after infection with SARS-CoV-2. To date care for people with long covid has centred around multidisciplinary rehabilitation, self care and self pacing. No pharmacotherapy has been […]

POST-ACUTE SEQUELAE OF COVID-19: CHARACTERIZATION, COMORBIDITIES, AND BIOMARKERS IN A DIVERSE COHORT

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Emily Struttmann, Anish Shah, Matthew Moreida, et. al. doi: https://doi.org/10.1101/2024.06.20.24308901 Abstract Introduction Post-acute sequelae of COVID-19 (PASC) is causing a silent pandemic in the U.S. Gulf South, a part of flyover U.S. where patients are quietly withdrawing from the workforce and largely disconnected from the advocacy resources growing in more affluent regions[1]. To date, there is no clinical test to diagnose PASC […]

Long COVID-19 is linked to chronic pain conditions

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Therapies for pain conditions like fibromyalgia provide clues for helping those with long COVID Many patients continue to struggle in the wake of the pandemic as they grapple with ongoing symptoms triggered by COVID-19 infection, a condition commonly known as long COVID. However, the onset of symptoms such as brain fog, fatigue, headache, and other […]

Supreme Court Turns Away COVID-19 Vaccine Appeals

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TUESDAY, JUN 25, 2024 – Authored by Zachary Stieber via The Epoch Times  U.S. Supreme Court justices on June 24 rejected appeals brought over COVID-19 vaccines by Children’s Health Defense (CHD), a nonprofit founded by Robert F. Kennedy Jr., an independent candidate running for president. The nation’s top court rejected an appeal seeking to overturn […]

Patients with neurological disease are likelier to die after COVID, finds study

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by Geoff McMaster, University of Alberta People with neurological disease have a greater chance of death after contracting COVID-19, according to a new University of Alberta study. The research also confirms a higher risk of developing new neurological disorders after COVID infection. “For those who have neurological diseases—if you have Parkinson’s, if you have dementia, if you […]

Asymptomatic COVID-19 Infection-Induced Rhabdomyolysis in the Backdrop of Statin-Cyclosporine Drug Interaction

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Vivek Nayak M • FNU Bipasha • Kotresha Neelakantappa, DOI: 10.7759/cureus.68127  Abstract Rhabdomyolysis involves skeletal muscle breakdown leading to high serum creatine kinase (CK) levels and myoglobinuria. Here, we report the case of a middle-aged man who developed rhabdomyolysis, resulting in acute kidney injury (AKI) over pre-existing chronic kidney disease (stage 3a) secondary to focal segmental glomerulosclerosis (primary FSGS), during […]

Study Finds Alarming Surge In Deaths From Neurological Disease Among Young Adults

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ZeroHedge June 24, 2024 A recent preprint study which relies on extensive data from the Centers for Disease Control and Prevention (CDC) paints a concerning picture of the neurological health landscape in the United States. The study, which focuses on those aged 15-44, reveals a disturbing increase in deaths from neurological diseases both as the primary cause and among multiple […]

Two studies unveil key insights into long COVID

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by University of Texas at Austin Health care providers are learning critical new information to help improve care for patients with long COVID, thanks to a pair of recent studies out of the Post-COVID-19 Program at UT Health Austin, the clinical practice of Dell Medical School at the University of Texas at Austin. Over the past […]

Increased frequency and mortality in persons with neurological disorders during COVID-19 

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Candace M Marsters, Jeffrey A Bakal, Grace Y Lam, Finlay A McAlister, Christopher Power, Brain, awae117, https://doi.org/10.1093/brain/awae117, 20 April 2024 Abstract Determining the frequency and outcomes of neurological disorders associated with coronavirus disease 2019 (COVID-19) is imperative for understanding risks and for recognition of emerging neurological disorders. We investigated the susceptibility and impact of severe acute respiratory syndrome coronavirus 2 […]