SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans

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Authors: Jackson S. Turner, Wooseob Kim, Elizaveta Kalaidina, Charles W. Goss, Adriana M. Rauseo, Aaron J. Schmitz, Lena Hansen, Alem Haile, Michael K. Klebert, Iskra Pusic, Jane A. O’Halloran, Rachel M. Presti & Ali H. Ellebedy  Nature volume 595, pages421–425 (2021) Abstract Long-lived bone marrow plasma cells (BMPCs) are a persistent and essential source of protective antibodies1,2,3,4,5,6,7. Individuals who have recovered from COVID-19 have a substantially lower risk of reinfection with […]

A Case Of Shrunken Brains: How Covid-19 May Damage Brain Cells

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Authors: William A. Haseltine Forbes March 22, 2022 Thanks to a new study from the UK we are now beginning to uncover the effects of SARS-CoV-2 infections in the brain. Comparing brain volume before and after individuals were exposed to SARS-CoV-2, this study documents significant cortical gray matter loss, equivalent to nearly 10 years of aging. Gweanaelle […]

Covid infection associated with a greater likelihood of Type 2 diabetes, according to review of patient records

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Authors: Lenny Bernstein – March 21, 2022 The Washington Post People who had covid-19 were at greater risk of developing Type 2 diabetes within a year than those who managed to avoid the coronavirus, according to a large review of patient records released Monday. The finding is true even for people who had less severe or asymptomatic […]

Massive gastrointestinal bleeding in a patient with COVID-19

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Authors: Mahmoud Mohamed,a,⁎Mahmoud Nassar,bNso Nso,b and Mostafa Alfishawyc Arab J Gastroenterol. 2021 Jun; 22(2): 177–179.Published online 2021 May 14.  doi: 10.1016/j.ajg.2021.05.00 8PMCID: PMC8118668PMID: 34090835 Abstract Despite the emerging data about the thrombophilic effect of the novel coronavirus [1] , the relation between coagulation disorders and the COVID-19 pandemic is still not well understood. Various studies pointed to the significant role of the COVID-19 […]

SARS-CoV-2 mRNA Vaccination-Associated Myocarditis in Children Ages 12-17: A Stratified National Database Analysis

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Authors: RALPH TURCHIANO   SEPTEMBER 8, 2021 •  Abstract Establishing the rate of post-vaccination cardiac myocarditis in the 12-15 and 16-17-year-old population in the context of their COVID-19 hospitalization risk is critical for developing a vaccination recommendation framework that balances harms with benefits for this patient demographic. Design, Setting and Participants: Using the Vaccine Adverse Event Reporting […]

COVCOG 1: Factors Predicting Physical, Neurological and Cognitive Symptoms in Long COVID in a Community Sample. A First Publication From the COVID and Cognition Study

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Authors: Panyuan Guo1, Alvaro Benito Ballesteros1, Sabine P. Yeung1, Ruby Liu1, Arka Saha1, Lyn Curtis2, Muzaffer Kaser3,4, Mark P. Haggard1 and Lucy G. Cheke1* Since its first emergence in December 2019, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has evolved into a global pandemic. Whilst often considered a respiratory disease, a large proportion of COVID-19 patients report neurological […]

7 in 10 long COVID patients are dealing with memory and concentration problems

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Authors: Study Finds MARCH 17, 2022 The vast majority of people dealing with “long COVID” are experiencing memory and concentration problems — months after their actual coronavirus infection, a new study warns. Researchers at the University of Cambridge say seven in 10 people experiencing the lingering effects of COVID are now struggling mentally. The study […]

Efficacy of Ivermectin Treatment on Disease Progression Among Adults With Mild to Moderate COVID-19 and Comorbidities

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The I-TECH Randomized Clinical Trial February 18, 2022 Authors: Steven Chee Loon Lim, MRCP1; Chee Peng Hor, MSc2,3; Kim Heng Tay, MRCP4; et alAnilawati Mat Jelani, MMed5; Wen Hao Tan, MMed6; Hong Bee Ker, MRCP1; Ting Soo Chow, MRCP7;  Masliza Zaid, MMed8; Wee Kooi Cheah, MRCP6; Han Hua Lim, MRCP9; Khairil Erwan Khalid, MRCP10; Joo Thye Cheng, MRCP2; Hazfadzila Mohd Unit, MRCP11;  Noralfazita  An, MMed12; Azraai Bahari Nasruddin, MRCP13; Lee Lee Low, MRCP14; Song Weng Ryan Khoo, MRCP15; Jia Hui Loh, MRCP16; Nor Zaila Zaidan, MMed17; Suhaila Ab Wahab, MMed18; Li Herng Song, MD19; Hui Moon Koh, MClinPharm20; Teck Long King, BPharm21; Nai Ming Lai, MRCPCH22; Suresh Kumar Chidambaram, MRCP4; Kalaiarasu M. Peariasamy, MSc23;  for the I-TECH Study Group Article Information Abstract Importance  Ivermectin, an inexpensive and widely available antiparasitic drug, is […]

SARS-CoV-2 vaccine-associated-tinnitus: A review

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Authors: Syed HassanAhmedaSummaiyyaWaseemaTaha GulShaikhaNashwa AbdulQadiraSarush AhmedSiddiquiaIrfanUllahbAbdulWarisbZohaibYousafc Annals of Medicine and Surgery Volume 75, March 2022, 103293 Abstract The global vaccination drive against severe acute respiratory syndrome coronavirus-2 is being pursued at a historic pace. Unexpected adverse effects have been reported following vaccination, including thrombotic thrombocytopenia, myocarditis, amongst others. More recently, some cases of tinnitus are reported post-vaccination. According […]

SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment

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aUTHORS: Chien-Ting Wu,1,13Peter V. Lidsky,2,13Yinghong Xiao,2,13Ivan T. Lee,3,4,5,13Ran Cheng,1,6,13Tsuguhisa Nakayama,5,7,13Sizun Jiang,3,13Janos Demeter,1Romina J. Bevacqua,8Charles A. Chang,8,9,10,11Robert L. Whitener,8Anna K. Stalder,12Bokai Zhu,3Han Chen,3 Cell Metab. 2021 Aug 3; 33(8): 1565–1576.e5.Published online 2021 May18. doi: 10.1016/j.cmet.2021.05.013 :  PMC8130512PMID: 34081912 Abstract Emerging evidence points toward an intricate relationship between the pandemic of coronavirus disease 2019 (COVID-19) and diabetes. While preexisting diabetes is […]