Potential molecular mechanisms of chronic fatigue in long haul COVID and other viral diseases

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Carl Gunnar Gottschalk, Daniel Peterson, Jan Armstrong, Konstance Knox & Avik Roy  Infectious Agents and Cancer volume 18, Article number: 7 (2023) Cite this article, A Correction to this article was published on 24 April 2023 Abstract Historically, COVID-19 emerges as one of the most devastating diseases of humankind, which creates an unmanageable health crisis worldwide. Until now, this disease costs millions of lives and continues to paralyze […]

COVID-19 and emerging spinal cord complications: A systematic review

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Ritwick Mondal,a Shramana Deb,b Gourav Shome,c Upasana Ganguly,a Durjoy Lahiri,a,d,⁎ and Julián Benito-Leóne,f,g,⁎⁎ Mult Scler Relat Disord. 2021 Jun; 51: 102917.Published online 2021 Mar 21. doi: 10.1016/j.msard.2021.102917 PMCID: PMC7981271 PMID: 33845350 Abstract Background : Spinal cord complications associated with coronavirus infectious disease of 2019 (COVID-19) are being widely reported. The purpose of this systematic review was to summarize so far available pieces of evidence documenting de novo novel severe […]

Treatment of Long COVID symptoms with triple anticoagulant therapy

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Gert J Laubscher, M Asad Khan, Chantelle Venter, Jan H Pretorius, and 2 more, This is a preprint; it has not been peer reviewed by a journal. https://doi.org/10.21203/rs.3.rs-2697680/v1 Research Square Abstract Background: Fibrin(ogen) amyloid microclots and platelet hyperactivation are key pathological findings in patients with acute COVID-19 infection and also in those with Long COVID/Post-Acute Sequelae […]

Spinal cord involvement in COVID-19: A review

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Ravindra Kumar Garg,1 Vimal Kumar Paliwal,2 and Ankit Gupta2 J Spinal Cord Med. 2023; 46(3): 390–404. Published online 2021 Mar 11. doi: 10.1080/10790268.2021.1888022 PMCID: PMC10114972PMID: 33705268 Abstract Context: Recent literature points towards myelitis, like encephalitis, as a common central nervous system complication of COVID-19. This review elaborates on disorders of the spinal cord caused by the SARS-CoV-2 virus. Objectives: To review the published data about […]

Unraveling long COVID: Here’s what scientists who study the illness want to find out

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September 9, 2023, By Will Stone NPR Newsletter Researchers looking for root causes of long COVID work in the autopsy suite inside the Clinical Center at the National Institute of Health in Bethesda, Maryland. Valerie Plesch/Bloomberg via Getty Images For people suffering from long COVID’s often disabling symptoms, including intense fatigue, breathing troubles, cognitive issues and heart […]

Study identifies risk factors for long-haul COVID disease in adults

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by Lynda De Widt, Mayo Clinic SEPTEMBER 14, 2023 Medical Xpress Mayo Clinic researchers have identified risk factors that can cause adult COVID-19 patients to suffer symptoms that linger for months or years. The condition is often referred to as long-haul COVID. The findings are reported in the Journal of Investigative Medicine. Researchers surveyed more than 3,000 […]

Long COVID: Where Are We in 2023?

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Hariharan Regunath, MD, Vamsi P. Guntur, MD Mo Med. 2023 Mar-Apr; 120(2): 102–105.PMCID: PMC10121126 PMID: 37091941 Copyright and License information PMC Disclaimer NCBI The term “COVID Long-Hauler” or “Long-Haul COVID” was first created by patients within few months of the onset of the pandemic.1,2 The first publication of persistent symptoms following acute COVID-19 was from Italy in July 2020, where-in, […]

Large study provides scientists with deeper insight into long COVID symptoms

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May 25, 2023, National Heart, Lung & Blood Institute NIH-funded research effort identifies most common symptoms, potential subgroups, and initial symptom-based scoring system – with aim of improving future diagnostics and treatment Initial findings from a study of nearly 10,000 Americans, many of whom had COVID-19, have uncovered new details about long COVID, the post-infection […]

Chronic Spontaneous Urticaria Following COVID-19 Vaccination: A Case Report and Discussion on Allergic Reactions and Vaccine Safety

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Jesus Ivan Martinez-Ortega1 and Felipe de Jesus Perez Hernandez2 Cureus. 2023 Sep; 15(9): e44860. Published online 2023 Sep 7. doi: 10.7759/cureus.44860 PMCID: PMC10560097 PMID: 37809203 Abstract This case report examines a rare occurrence of chronic spontaneous urticaria (CSU) following the administration of the CoronaVac vaccine for COVID-19. The patient developed persistent urticarial lesions that appeared and disappeared over an extended period after […]

Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

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Suo-wen Xu, Iqra Ilyas & Jian-ping Weng  Acta Pharmacologica Sinica volume 44, pages695–709 (2023) Cite this article 17 October 2022 Abstract The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is still raging. However, the pathophysiology of acute and post-acute manifestations of COVID-19 (long COVID-19) is understudied. Endothelial cells are sentinels lining the innermost layer of blood vessel that […]