Comorbidity and its Impact on Patients with COVID-19

Posted on | Posted on John Murphy | Leave a Comment on Comorbidity and its Impact on Patients with COVID-19

Authors: Adekunle Sanyaolu 1, Chuku Okorie 2, Aleksandra Marinkovic 3, Risha Patidar 3, Kokab Younis 4, Priyank Desai 5, Zaheeda Hosein 6, Inderbir Padda 7, Jasmine Mangat 6, Mohsin Altaf 8 Abstract A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in Wuhan, China, in December 2019. Since then, the virus has made its way across the globe to affect over 180 countries. SARS-CoV-2 has infected humans in all age […]

Comparative study of hospitalized children with acute respiratory distress syndrome caused by SARS-CoV-2 and influenza virus

Posted on | Posted on John Murphy | Leave a Comment on Comparative study of hospitalized children with acute respiratory distress syndrome caused by SARS-CoV-2 and influenza virus

Authors: Xinghua Liu, Wei Li, Bo Zhang, Yan Guo, Zhao Hu, Cao Peng, Xiao Lei, Qunying Luo, Qiong hang, Wei Deng, Juanjuan Wang, Jianqiao Tang, Yunqiao Li & Jianying Chen BMC Infectious Diseases volume 21, Article number: 412 (2021)  Abstract Background Since the outbreak of coronavirus disease 2019 in December 2019, more than 8 million cases have occurred worldwide as of June 16, 2020. However, it is important to distinguish COVID-19 from other respiratory infectious […]

COVID-19: an update and cardiac involvement

Posted on | Posted on John Murphy | Leave a Comment on COVID-19: an update and cardiac involvement

Authors: Nizar R. Alwaqfi & Khalid S. Ibrahim  Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through angiotensin converting enzyme 2 receptors, leading to coronavirus disease (COVID-19)-related pneumonia, and also causing acute cardiac injury and chronic damage to the cardiovascular system. The purpose of this review is primarily reviewing the COVID-19 disease, including pathogen, […]

Virology, transmission, and pathogenesis of SARS-CoV-2

Posted on | Posted on John Murphy | Leave a Comment on Virology, transmission, and pathogenesis of SARS-CoV-2

Authors: Muge Cevik, clinical lecturer1 2,  Krutika Kuppalli, assistant professor3,  Jason Kindrachuk, assistant professor of virology4,  Malik Peiris, professor of virology5 What you need to know SARS-CoV-2 is genetically similar to SARS-CoV-1, but characteristics of SARS-CoV-2—eg, structural differences in its surface proteins and viral load kinetics—may help explain its enhanced rate of transmission In the respiratory […]

Severe covid-19 pneumonia: pathogenesis and clinical management

Posted on | Posted on John Murphy | Leave a Comment on Severe covid-19 pneumonia: pathogenesis and clinical management

Authors: Amy H Attaway, assistant professor of medicine, associate director, COPD center1,  Rachel G Scheraga, assistant professor of medicine1 2,  Adarsh Bhimraj, head, section of neurological infections; staff, infectious diseases1,  Michelle Biehl, associate staff, pulmonary and critical care medicine; director, post ICU recovery clinic1,  Umur Hatipoğlu, associate professor of medicine; director, respiratory therapy; director, COPD center1 […]

Neurologic Features in Severe SARS-CoV-2 Infection

Posted on | Posted on John Murphy | Leave a Comment on Neurologic Features in Severe SARS-CoV-2 Infection

Authors: Julie Helms, M.D., Ph.D., Stéphane Kremer, M.D., Ph.D., Hamid Merdji, M.D., Raphaël Clere-Jehl, M.D., Malika Schenck, M.D., Christine Kummerlen, M.D., Olivier Collange, M.D., Ph.D., Clotilde Boulay, M.D., Samira Fafi-Kremer, Pharm.D., Ph.D., Mickaël Ohana, M.D., Ph.D., Mathieu Anheim, M.D., Ph.D. Strasbourg University Hospital, Strasbourg, France, Ferhat Meziani, M.D., Ph.D.University of Strasbourg, Strasbourg, France Reported here […]

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents A Systematic Review

Posted on | Posted on John Murphy | Leave a Comment on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents A Systematic Review

Authors: Riccardo Castagnoli, MD1,2; Martina Votto, MD1,2; Amelia Licari, MD1,2; et al Key Points Question  What are the clinical features of pediatric patients with coronavirus disease 2019 (COVID-19)? Findings  In this systematic review of 18 studies with 1065 participants, most pediatric patients with SARS-CoV-2 infection presented with fever, dry cough, and fatigue or were asymptomatic; 1 infant presented with pneumonia, complicated by shock and kidney failure, […]

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19) – anatomic pathology perspective on current knowledge

Posted on | Posted on John Murphy | Leave a Comment on Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19) – anatomic pathology perspective on current knowledge

Authors: Sambit K. Mohanty, Abhishek Satapathy, Machita M. Naidu, Sanjay Mukhopadhyay, Shivani Sharma, Lisa M. Barton, Edana Stroberg, Eric J. Duval, Dinesh Pradhan, Alexandar Tzankov & Anil V. Parwani  Abstract Background The world is currently witnessing a major devastating pandemic of Coronavirus disease-2019 (COVID-19). This disease is caused by a novel coronavirus named Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). It primarily affects the respiratory tract and […]

COVID-19: Current understanding of its Pathophysiology, Clinical presentation and Treatment

Posted on | Posted on John Murphy | Leave a Comment on COVID-19: Current understanding of its Pathophysiology, Clinical presentation and Treatment

Authors: Anant Parasher Abstract Background The severe acute respiratory syndrome (SARS) coronavirus-2 is a novel coronavirus belonging to the family Coronaviridae and is now known to be responsible for the outbreak of a series of recent acute atypical respiratory infections originating in Wuhan, China. The disease caused by this virus, termed coronavirus disease 19 or simply […]

The role of extracorporeal membrane oxygenation in critically ill patients with COVID-19: a narrative review

Posted on | Posted on John Murphy | Leave a Comment on The role of extracorporeal membrane oxygenation in critically ill patients with COVID-19: a narrative review

Authors: Shiqian Huang, Shuai Zhao, Huilin Luo, Zhouyang Wu, Jing Wu, Haifa Xia & Xiangdong Chen BMC Pulmonary Medicine volume 21, Article number: 116 (2021) Abstract Extracorporeal life support treatments such as extracorporeal membrane oxygenation (ECMO) have been recommended for the treatment of severe acute respiratory distress syndrome (ARDS) patients with coronavirus disease 2019 (COVID-19). To date, many countries, including China, have adopted ECMO as a treatment for […]