Persistent symptoms and clinical findings in adults with post-acute sequelae of COVID-19/post-COVID-19 syndrome in the second year after acute infection: population-based, nested case-control study

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Raphael S. Peter, Alexandra Nieters, Siri Göpel, et. al.,doi: https://doi.org/10.1101/2024.05.22.24307659 Abstract Objective To assess risk factors for persistence vs improvement and to describe clinical characteristics and diagnostic evaluation of subjects with post-acute sequelae of COVID-19/post-COVID-19 syndrome (PCS) persisting for more than one year. Design Nested population-based case-control study. Setting Comprehensive outpatient assessment, including neurocognitive, cardiopulmonary exercise, and laboratory testing in four university health centres in […]

The Concealing Effect of COVID-19: Unveiling the Surge in Community-Acquired Infections and Its Association With Diabetic Ketosis During the Pandemic

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Abstract Background Some studies suggest that the SARS-CoV-2 pandemic has contributed to diverting attention from other community-acquired infections (CAIs), leading to an increase in their incidence and severity. Our study aimed to describe and compare clinical features of CAI before and during the pandemic as a factor precipitating diabetes ketoacidosis (DKA). Methodology We included 250 […]

The Assessment of Functional Status Among COVID-19 Patients at Three Months Using Pulmonary Function Tests

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Mohini Asija • Shaveta Dahiya • Rohit Parsad • Sanjay Fotedar • Rohit Sharma • Vikas Bhatthi  May 28, 2024, DOI: 10.7759/cureus.61221  Abstract Introduction The coronavirus disease 2019 (COVID-19) pandemic has impacted the lives of thousands of patients worldwide with many patients having residual symptoms months after the acute infection. The severity of lung involvement ranges from mild asymptomatic to severe acute respiratory distress syndrome (ARDS), […]

Natural course of post-COVID symptoms in adults and children

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Aya Sugiyama, Toshiro Takafuta, Tomoki Sato, et. al. Scientific Reports volume 14, Article number: 3884 (2024)  Abstract More than 200 million COVID-19 survivors have lasting symptoms after recovering, but the duration and related risk factors remain uncertain. This study focused on all 6551 patients diagnosed with COVID-19 at a medical institution in Hiroshima from March 2020 to July 2022. In November 2022, a […]

Brain abnormalities in survivors of COVID-19 after 2-year recovery: a functional MRI study

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Yimiao Zhao , Qiongdan Liang , Zhendong Jiang, et. al, May 09, 2024DOI: https://doi.org/10.1016/ j.lanwpc.2024.101086 Summary Background A variety of symptoms, particularly cognitive, psychiatric and neurological symptoms, may persist for a long time among individuals recovering from COVID-19. However, the underlying mechanism of these brain abnormalities remains unclear. This study aimed to investigate the long-term neuroimaging effects […]

Cognition and Memory after Covid-19 in a Large Community Sample

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Authors: Adam Hampshire, Ph.D., Adriana Azor, Ph.D, et. al. Published February 28, 2024, N Engl J Med 2024;390:806-818, DOI: 10.1056/NEJMoa2311330 VOL. 390 NO. 9 BACKGROUND Cognitive symptoms after coronavirus disease 2019 (Covid-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are well-recognized. Whether objectively measurable cognitive deficits exist and how long they persist are unclear. METHODS We invited 800,000 adults in a study in […]

New study reveals insights into COVID-19 antibody response durability

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University of Maryland School of Medicine, 2024 Researchers at the Institute of Human Virology (IHV) at the University of Maryland School of Medicine have published a new study in the Journal of Infectious Diseases investigating the antibody response following SARS-CoV-2 infection. Long-lived plasma cells are responsible for durable antibody responses that persist for decades after immunization or infection. For example, infection […]

Scientists Decode Deadly Blood Clot Disorder Triggered by COVID Vaccines

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By FLINDERS UNIVERSITY MAY 26, 2024 Researchers from Flinders University, along with international experts, have discovered that the PF4 antibodies causing VITT after adenovirus vector-based COVID-19 vaccination share identical molecular signatures with those found in similar cases following natural adenovirus infection. This finding, using a new approach developed at Flinders, has significant implications for understanding the genetic […]

People with long COVID have distinct patterns of inflammation detectable in the blood, which could potentially be targeted with immune therapies.

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Findings from the largest UK study of patients hospitalized with SARS-CoV-2 infection show that long COVID leads to ongoing inflammation which can be detected in the blood. In an analysis of more than 650 people who had been hospitalized with severe COVID-19, patients with prolonged symptoms showed evidence of immune system activation. The exact pattern […]

Arizona researcher publishes study on COVID-19 vaccine and tinnitus

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By: Melissa Blasius, May 24, 2024 Preexisting health conditions found to be a risk factor for developing vaccine-related tinnitus or hearing loss. A newly published scientific study about the COVID-19 vaccine found people with certain preexisting medical conditions were more likely to report ringing in the ears after getting immunized. A newly published scientific study about […]