The COVID-19 Long Haul Foundation – Page 160 – Treatment, Referral & Educational Support for Illnesses & Vaccine Injury

Severe covid-19 pneumonia: pathogenesis and clinical management

August 11, 2021 | John Murphy | Leave a Comment

Authors: Amy H Attaway, assistant professor of medicine, associate director, COPD center1, Rachel G Scheraga, assistant professor of medicine1 2, Adarsh Bhimraj, head, section of neurological infections; staff, infectious diseases1, Michelle Biehl, associate staff, pulmonary and critical care medicine; director, post ICU recovery clinic1, Umur Hatipoğlu, associate professor of medicine; director, respiratory therapy; director, COPD center1 […]

Neurologic Features in Severe SARS-CoV-2 Infection

August 11, 2021 | John Murphy | Leave a Comment

Authors: Julie Helms, M.D., Ph.D., Stéphane Kremer, M.D., Ph.D., Hamid Merdji, M.D., Raphaël Clere-Jehl, M.D., Malika Schenck, M.D., Christine Kummerlen, M.D., Olivier Collange, M.D., Ph.D., Clotilde Boulay, M.D., Samira Fafi-Kremer, Pharm.D., Ph.D., Mickaël Ohana, M.D., Ph.D., Mathieu Anheim, M.D., Ph.D. Strasbourg University Hospital, Strasbourg, France, Ferhat Meziani, M.D., Ph.D.University of Strasbourg, Strasbourg, France Reported here […]

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents A Systematic Review

August 11, 2021 | John Murphy | Leave a Comment

Authors: Riccardo Castagnoli, MD1,2; Martina Votto, MD1,2; Amelia Licari, MD1,2; et al Key Points Question What are the clinical features of pediatric patients with coronavirus disease 2019 (COVID-19)? Findings In this systematic review of 18 studies with 1065 participants, most pediatric patients with SARS-CoV-2 infection presented with fever, dry cough, and fatigue or were asymptomatic; 1 infant presented with pneumonia, complicated by shock and kidney failure, […]

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19) – anatomic pathology perspective on current knowledge

August 11, 2021 | John Murphy | Leave a Comment

Authors: Sambit K. Mohanty, Abhishek Satapathy, Machita M. Naidu, Sanjay Mukhopadhyay, Shivani Sharma, Lisa M. Barton, Edana Stroberg, Eric J. Duval, Dinesh Pradhan, Alexandar Tzankov & Anil V. Parwani Abstract Background The world is currently witnessing a major devastating pandemic of Coronavirus disease-2019 (COVID-19). This disease is caused by a novel coronavirus named Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). It primarily affects the respiratory tract and […]

COVID-19: Current understanding of its Pathophysiology, Clinical presentation and Treatment

August 11, 2021 | John Murphy | Leave a Comment

Authors: Anant Parasher Abstract Background The severe acute respiratory syndrome (SARS) coronavirus-2 is a novel coronavirus belonging to the family Coronaviridae and is now known to be responsible for the outbreak of a series of recent acute atypical respiratory infections originating in Wuhan, China. The disease caused by this virus, termed coronavirus disease 19 or simply […]

The role of extracorporeal membrane oxygenation in critically ill patients with COVID-19: a narrative review

August 11, 2021 | John Murphy | Leave a Comment

Authors: Shiqian Huang, Shuai Zhao, Huilin Luo, Zhouyang Wu, Jing Wu, Haifa Xia & Xiangdong Chen BMC Pulmonary Medicine volume 21, Article number: 116 (2021) Abstract Extracorporeal life support treatments such as extracorporeal membrane oxygenation (ECMO) have been recommended for the treatment of severe acute respiratory distress syndrome (ARDS) patients with coronavirus disease 2019 (COVID-19). To date, many countries, including China, have adopted ECMO as a treatment for […]

The Severe Acute Respiratory Syndrome

August 11, 2021 | John Murphy | Leave a Comment

Authors: Joseph S.M. Peiris, M.D., D.Phil., Kwok Y. Yuen, M.D., Albert D.M.E. Osterhaus, Ph.D., and Klaus Stöhr, Ph.D. The severe acute respiratory syndrome (SARS) is responsible for the first pandemic of the 21st century. Within months after its emergence in Guangdong Province in mainland China, it had affected more than 8000 patients and caused 774 deaths in 26 […]

Rapid detection of novel coronavirus/Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) by reverse transcription-loop-mediated isothermal amplification

August 11, 2021 | John Murphy | Leave a Comment

Authors: Laura E. Lamb ,Sarah N. Bartolone,Elijah Ward,Michael B. Chancellor Abstract Novel Corona virus/Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 or 2019-nCoV), and the subsequent disease caused by the virus (coronavirus disease 2019 or COVID-19), is an emerging global health concern that requires a rapid diagnostic test. Quantitative reverse transcription PCR (qRT-PCR) is currently the standard […]

Pathophysiology of acute respiratory syndrome coronavirus 2 infection: a systematic literature review to inform EULAR points to consider

August 11, 2021 | John Murphy | Leave a Comment

Authors: Aurélie Najm1, http://orcid.org/0000-0003-1105-5640Alessia Alunno2, Xavier Mariette3,4, http://orcid.org/0000-0001-6612-7336Benjamin Terrier5,6, http://orcid.org/0000-0003-2406-161XGabriele De Marco7,8, Jenny Emmel9, Laura Mason9, Dennis G McGonagle7,10 and http://orcid.org/0000-0002-8411-7972Pedro M Machado11,12,13 Abstract Background The SARS-CoV-2 pandemic is a global health problem. Beside the specific pathogenic effect of SARS-CoV-2, incompletely understood deleterious and aberrant host immune responses play critical roles in severe disease. Our objective was to summarise the available information on the pathophysiology […]