Long COVID scientists try to unravel blood clot mystery

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May 15, 202312:15 AM ET By Anil Oza, Rebecca Ramirez, Emily Kwong, Gabriel Spitzer, Margaret Cirino, Berly McCoy, https://www.npr.org/2023/05/10/1175217130/long-covid-scientists-try-to-unravel-blood-clot-mystery As part of studying long COVID, graduate researcher Bradley Wade Hamilton separates out microclots from blood platelets in a solution. The federal COVID-19 public health emergency ended last week, but millions in the U.S. — and across the globe — are still dealing […]

Blood Clotting Proteins Might Help Predict Long COVID Brain Fog

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New research suggests that blood clotting from COVID infections could contribute to long-term brain fog and other cognitive issues By Sara Reardon on September 1, 2023 Scientific American Many people who have long COVID—a condition in which health issues persist months after infection—report struggling with “brain fog,” recurring memory and concentration lapses that make it difficult­­ to function […]

Increased risk of chronic fatigue and hair loss following COVID-19 in individuals with hypohidrotic ectodermal dysplasia

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Verena Hennig, Wolfgang Schuh, Antje Neubert, Dirk Mielenz, Hans-Martin Jäck & Holm Schneider Orphanet Journal of Rare Diseases volume 16, Article number: 373 (2021) Cite this article Abstract Background Hypohidrotic ectodermal dysplasia (HED) is a group of genodermatoses in which deficient ectodysplasin A signalling leads to maldevelopment of skin appendages, various eccrine glands, and teeth. Individuals with HED often have disrupted epithelial barriers and, therefore, were suspected to […]

An overview of human proteins and genes involved in SARS-CoV-2 infection

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Zohreh Jahanafrooz,a,⁎ Zhishan Chen,b Jiandong Bao,c Hongzhi Li,d Loren Lipworth,b and Xingyi Guob,e,⁎Gene. 2022 Jan 15; 808: 145963. Published online 2021 Sep 14. doi: 10.1016/j.gene.2021.145963 PMCID: PMC8437745PMID: 34530086 Graphical abstract A summarized view of recent findings of host proteins interacting with SARS-CoV-2 and genes containing associated variants with COVID-19 susceptibility and severity. The left side of the figure (A) shows host protein interactors (blue wrote) for […]

Disruption of the blood-brain barrier due to long COVID

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Bhavana Kunkalikar Jan 27 2023 Reviewed by Aimee Molineux, https://doi.org/10.21203/rs.3.rs-2069710/v2 In a recent study posted to the Research Square* preprint server, researchers explored the destruction of the blood-brain barrier (BBB) due to cognitive impairment associated with long coronavirus disease (COVID). Background Studies have demonstrated microvascular injuries observed in the brains of deceased severe acute respiratory syndrome coronavirus 2 […]

Saliva changes in composition associated to COVID-19: a preliminary study

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Alberto Muñoz-Prieto, Ivana Rubić, Juan Carlos Gonzalez-Sanchez, Josipa Kuleš, Silvia Martínez-Subiela, José Joaquín Cerón, Enrique Bernal, Alberto Torres-Cantero, María Rosario Vicente-Romero, Vladimir Mrljak & Asta Tvarijonaviciute  Scientific Reports volume 12, Article number: 10879 (2022) Cite this article Abstract The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2), is usually associated with a wide variety of clinical presentations from asymptomatic to severe cases. The use of […]

Alopecia Areata after COVID-19 Vaccines

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Lucia Genco,* Mariateresa Cantelli, Matteo Noto, Teresa Battista, Angela Patrì, Gabriella Fabbrocini, and Maria Vastarella Skin Appendage Disord. 2023 Mar; 9(2): 141–143. Published online 2023 Jan 19. doi: 10.1159/000528719 PMCID: PMC9892995 PMID: 36926281 Abstract Introduction Alopecia areata (AA) is a common autoimmune disease characterized by non-scarring hair loss. New onsets of AA have been associated with coronavirus disease 2019 (COVID-19). Various skin diseases have already been […]

Structural biology of SARS-CoV-2 and implications for therapeutic development

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Haitao Yang & Zihe Rao  Nature Reviews Microbiology volume 19, pages685–700 (2021) Cite this article Abstract The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an unprecedented global health crisis. However, therapeutic options for treatment are still very limited. The development of drugs that target vital proteins in the viral life cycle is a feasible approach […]

Headaches and COVID-19 Long-Haulers: What to Know

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September 16, 2021 / Brain & Spine The Cleveland Clinic Skull-pounding headaches can continue for weeks or even months after you test positive for COVID-19, with around-the-clock pain separated only by periods of agonizing and extreme spikes. It’s one of the most common symptoms being experienced by a group known as COVID-19 long-haulers, or those with lingering issues […]

UK scientists find link between proteins related to blood clots and long Covid

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Biomarker discovery indicates that sufferers from brain fog and fatigue post-virus could be treated with anticoagulants Oksana Pyzik 31 Aug 2023 The Guardian Scientists have identified molecular signatures in the blood that are linked to brain fog, other cognitive problems and fatigue in patients who are diagnosed with long Covid after catching the virus. Raised levels of […]