Filtration Efficiency, Effectiveness, and Availability of N95 Face Masks for COVID-19 Prevention

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Authors: Caitlin M. Dugdale, MD1,2; Rochelle P. Walensky, MD, MPH In March 2020, the soaring number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections resulted in an unprecedented shortage of personal protective equipment (PPE) for clinicians and essential health care workers.1 The shortage was most profound among N95 masks. N95 respirators, named for their ability to filter 95% or more […]

Coronavirus Recovery: Breathing Exercises

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Authors: Peiting Lien, DPT, PT The coronavirus that causes COVID-19 attacks the lungs and respiratory system, sometimes resulting in significant damage. COVID-19 often leads to pneumonia and even acute respiratory distress syndrome (ARDS), a severe lung injury. Recovering lung function is possible but can require therapy and exercises for months after the infection is treated. “Working toward recovery […]

Viral dynamics in mild and severe cases of COVID-19

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Authors: Lancet Correspondence Coronavirus disease 2019 (COVID-19) is a new pandemic disease. We previously reported that the viral load of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) peaks within the first week of disease onset.1, 2 Findings from Feb, 2020, indicated that the clinical spectrum of this disease can be very heterogeneous.3 Here, we report the viral RNA […]

Long covid: How to define it and how to manage it

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Authors: Nikki Nabavi, editorial scholar “Profound fatigue” was a common symptom in most people with long covid, she said, but added that a wide range of other symptoms included cough, breathlessness, muscle and body aches, and chest heaviness or pressure, but also skin rashes, palpitations, fever, headache, diarrhoea, and pins and needles. “A very common […]

Coronavirus 2019 (COVID-19)- Using Ascorbic Acid and Zinc Supplementation (COVIDAtoZ)

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Authors: Milind Desai, M. D, Suma Thomas Principal Investigators: The Cleveland Clinic A Clinical Trail to see whether ascorbic acid and zinc gluconate which has limited side effect profile and is readily available over the counter can decrease the duration of symptoms seen in patients with new diagnosis of COVID-2019. A secondary purpose is to […]

Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study

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Authors: Tao Chen, doctor1,  Di Wu, doctor1,  Huilong Chen, doctor1,  Weiming Yan, research associate1,  Danlei Yang, doctor2,  Guang Chen, doctor1,  Ke Ma, doctor1,  Dong Xu, doctor1,  Haijing Yu, doctor1,  Hongwu Wang, doctor1,  Tao Wang, doctor2,  Wei Guo, doctor1,  Jia Chen, doctor1,  Chen Ding, doctor1,  Xiaoping Zhang, doctor1,  Jiaquan Huang, doctor1,  Meifang Han, doctor1,  Shusheng Li, […]

The hallmarks of COVID-19 disease

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Authors: Daolin Tang ,Paul Comish,Rui Kang  Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that has caused a worldwide pandemic of the human respiratory illness COVID-19, resulting in a severe threat to public health and safety. Analysis of the genetic tree suggests that SARS-CoV-2 belongs to the same Betacoronavirus group as severe acute respiratory syndrome coronavirus […]

Persistent Symptoms in Patients After Acute COVID-19

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Authors: Angelo Carfì, MD1; Roberto Bernabei, MD1; Francesco Landi, MD, PhD1; et al In Italy, a large proportion of patients with coronavirus disease 2019 (COVID-19) presented with symptoms (71.4% of 31 845 confirmed cases as of June 3, 2020).1 Common symptoms include cough, fever, dyspnea, musculoskeletal symptoms (myalgia, joint pain, fatigue), gastrointestinal symptoms, and anosmia/dysgeusia.2–4 However, information is lacking on symptoms that persist after recovery. We assessed […]

Interim Clinical Guidance for Management of Patients with Confirmed Coronavirus Disease (COVID-19)

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Authors: CDC New information on potential for under-detection of occult hypoxemia by pulse oximetry, especially among persons with dark skin New information on dermatologic manifestations associated with COVID-19 New information on prolonged shedding of replication-competent SARS-CoV-2 in severely immunocompromised persons New information on reports of reinfection with variant viruses Clinical Presentation, Clinical Course, Laboratory and […]

Pathology and Pathogenesis of SARS-CoV-2 Associated with Fatal Coronavirus Disease, United States

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Authors: Roosecelis B. Martines, Jana M. Ritter1, Eduard Matkovic, Joy Gary, Brigid C. Bollweg, Hannah Bullock, Cynthia S. Goldsmith, Luciana Silva-Flannery, Josilene N. Seixas, Sarah Reagan-Steiner, Timothy Uyeki, Amy Denison, Julu Bhatnagar, Wun-Ju Shieh, Sherif R. Zaki, and COVID-19 Pathology Working Group An ongoing pandemic of coronavirus disease (COVID-19) is caused by infection with severe […]