SARS-CoV-2 particles promote airway epithelial differentiation and ciliation

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Julian Gonzalez-Rubio1* Vu Thuy Khanh Le-Trilling2 Lea Baumann1 Maria Cheremkhina1 Hannah Kubiza1 Anja E. Luengen1, 3 Sebastian Reuter3 Christian Taube3 Stephan Ruetten4 Daniela Duarte Campos5 Christian Cornelissen6 Mirko Trilling2 Anja Lena Thiebes1* Front. Bioeng. Biotechnology. , Sec. Tissue Engineering and Regenerative Medicine, Volume 11 – 2023 | doi: 10.3389/fbioe.2023.1268782 The Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which caused the coronavirus disease 2019 (COVID-19) pandemic, enters the […]

Diagnosis of venous thromboembolic diseases in people with covid-19: summary of updated NICE guidance

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BMJ 2023; 383 doi: https://doi.org/10.1136/bmj.p2204 (Published 12 October 2023)Cite this as: BMJ 2023;383:p2204, Sarah Boyce, senior technical analyst1,  Emma McFarlane, Susan Harrison, Terry McCormack What you need to know In venous thromboembolism, a blood clot usually forms in the deep veins of the legs or pelvis. This is known as deep vein thrombosis, and the blood clot can dislodge from these sites, […]

Hydroxychloroquine Associated With Lower COVID-19 Mortality: Study

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The French study included 30,202 patients. Zachary Stieber, 11/3/2023 Epoch Health People who received hydroxychloroquine were less likely to die than those who did not, according to a new study. Just 0.8 percent of patients at a facility in France who received hydroxychloroquine (HCQ) and an antibiotic died, compared to 4.8 percent of patients who did […]

Pathophysiology, diagnosis, and management of neuroinflammation in covid-19

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BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2022-073923 (Published 18 August 2023)Cite this as: BMJ 2023;382:e073923, Rachel L Brown123,  Laura Benjamin24,  Michael P Lunn12,  Tehmina Bharucha25,  Michael S Zandi12,  Chandrashekar Hoskote6,  Patricia McNamara2,  Hadi Manji1 Abstract Although neurological complications of SARS-CoV-2 infection are relatively rare, their potential long term morbidity and mortality have a significant impact, given the large numbers of infected patients. Covid-19 is […]

Interwoven challenges of covid-19, poor diet, and cardiometabolic health

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BMJ 2023; 383 doi: https://doi.org/10.1136/bmj-2023-076810 (Published 09 October 2023)Cite this as: BMJ 2023;383:e076810Read the full collection: Food for Thought 2023 Carmen Piernas, senior research fellow,  Jordi Merino, associate professor ,Correspondence to: C Piernas Carmen Piernas and Jordi Merino argue that suboptimal diet and poor metabolic health aggravated the covid-19 pandemic and require greater attention to increase population resilience and reduce health inequalities The covid-19 pandemic […]

Molecular mechanisms of COVID-19-induced pulmonary fibrosis and epithelial-mesenchymal transition

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Authors: Peng Pi1† Zhipeng Zeng1† Liqing Zeng1 Bing Han1 Xizhe Bai2 Shousheng Xu3*Front. Pharmacol., 03 August 2023, Sec. Respiratory Pharmacology, Volume 14 – 2023 | https://doi.org/10.3389/fphar.2023.1218059 As the outbreak of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first broke out in Hubei Province, China, at the end of 2019. It has brought great challenges and harms to global […]

Long covid: the doctors’ lives destroyed by an illness they caught while doing their jobs

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BMJ 2023; 382 doi: https://doi.org/10.1136/bmj.p1983 (Published 20 September 2023)Cite this as: BMJ 2023;382:p1983Linked OpinionAs a doctor with long covid, I feel abandoned by the NH Adele Waters, freelance journalist Unable to work or to play with their children, forced to sell their homes or facing insolvency—doctors with long covid deserve more support from the government and the NHS, writes Adele Waters When Kelly […]

Long covid—an update for primary care

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BMJ 2022; 378 doi: https://doi.org/10.1136/bmj-2022-072117 (Published 22 September 2022)Cite this as: BMJ 2022;378:e072117 Trisha Greenhalgh, Manoj Sivan, Brendan Delaney, Rachael Evans, Ruairidh Milne, What you need to know This article updates and extends a previous BMJ Practice Pointer published in August 2020 when almost no peer reviewed research or evidence based guidance on the condition was available.1 In this update we outline how clinicians might […]

COVID-19 mRNA Vaccines Reduce A Major Beneficial Bacteria, Gut Biodiversity: Research

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OCT 28, 2023 – Authored by Marina Zhang, The Epoch Times Opinion Piece Please Read–Bifidobacteria explained. Research has shown that COVID-19 mRNA vaccines reduce bacteria belonging to the Bifidobacteria genus, a common and beneficial gut bacteria. COVID vaccination is also linked to reduced gut biodiversity. Works by gastroenterologist Dr. Sabine Hazan, the CEO of ProgenaBiome, a […]

SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming

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Authors: Chien-Ting Wu , Peter V. Lidsky , Yinghong Xiao , Carlos Milla, Raul Andino, Peter K. Jackson  December 01, 2022DOI:https://doi.org/10.1016/j.cell.2022.11.030 Highlights Summary How SARS-CoV-2 penetrates the airway barrier of mucus and periciliary mucins to infect nasal epithelium remains unclear. Using primary nasal epithelial organoid cultures, we found that the virus attaches to motile cilia via the ACE2 […]