Coronavirus and the Nervous System


What is SARS-CoV-2 and COVID-19? What do we know about the effects of SARS-CoV-2 and COVID-19 on the nervous system? What are the immediate (acute) effects of SARS-CoV-2/COVID-19 on the brain? What is the typical recovery from COVID-19? What are possible long-term neurological complications of COVID-19? How do the long-term effects of SARS-CoV-2 infection/COVID-19 relate […]

Asthma drug brings hope for COVID-19 treatment


A steroid commonly used in asthma inhalers has the potential to prevent severe COVID-19 symptoms. It could treat the illness early on and help to reduce pressure on hospitals. Author Louisa Wright, Madelaine Pitt Date 13.04.2021 A common asthma medication that can be used at home might be an effective treatment for early COVID-19 in adults, according […]

Prophylaxis against covid-19: living systematic review and network meta-analysis


Authors: Jessica J Bartoszko, methodologist,1 ,*Reed A C Siemieniuk, methodologist, internist,1 ,*Elena Kum, methodologist,1 ,*Anila Qasim, methodologist,1 ,*Dena Zeraatkar, methodologist,1 ,*Long Ge, methodologist,2 ,*Mi Ah Han, methodologist,3Behnam Sadeghirad, assistant professor,1,4Arnav Agarwal, methodologist, internist,1,5Thomas Agoritsas, methodologist, internist,1,6Derek K Chu, methodologist, immunologist,1,7Rachel Couban, librarian,4Andrea J Darzi, methodologist,1Tahira Devji, methodologist,1Maryam Ghadimi, methodologist,1Kimia Honarmand, methodologist, critical care physician,8Ariel Izcovich, methodologist, internist,9Assem Khamis, data analyst,10Francois Lamontagne, methodologist, critical care physician,11Mark Loeb, methodologist, infectious disease physician,1,7Maura Marcucci, methodologist, internist,1,7Shelley L McLeod, methodologist, assistant professor,12,13Sharhzad […]

Toxic Epidermal Necrolysis Post COVID-19 Vaccination – First Reported Case


Authors: Mohamad Bakir, Hanan Almeshal, Rifah Alturki, Sulaiman Obaid, Areej Almazroo Published: August 16, 2021 Abstract Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a spectrum of acute, delayed-type hypersensitivity reactions that affect the skin and the mucous membranes. Medications are the culprit cause of these disorders in addition to infections and in very rare instances vaccinations. We report a case of […]

Pathological findings in organs and tissues of patients with COVID-19: A systematic review


Authors: Sasha Peiris 1 2, Hector Mesa 3, Agnes Aysola 4, Juan Manivel 5, Joao Toledo 1 2, Marcio Borges-Sa 6, Sylvain Aldighieri 1 2, Ludovic Reveiz 2 7 Abstract Background: Coronavirus disease (COVID-19) is the pandemic caused by SARS-CoV-2 that has caused more than 2.2 million deaths worldwide. We summarize the reported pathologic findings on biopsy and autopsy in patients with severe/fatal COVID-19 and documented the presence and/or effect of SARS-CoV-2 in all organs. […]

The latest on the coronavirus pandemic


Authors: By Ben Westcott, Adam Renton, Amy Woodyatt, Ed Upright, Meg Wagner, Melissa Macaya and Veronica Rocha, CNNUpdated 2:18 a.m. ET, August 22, 2020 What you need to know A CDC ensemble forecast now projects nearly 195,000 people will die from coronavirus in the United States by Sept. 12. As students return to US campuses, at least 15 states […]

Asthmatics at no higher risk getting or dying from COVID-19, assessment of studies consisting of 587,000 people shows


Authors: February 19, 2021Source:Taylor & Francis Group Summary: A review of 57 studies shows people with asthma had a 14 percent lower risk of getting COVID-19 and were significantly less likely to be hospitalized with the virus. A new study looking at how COVID-19 affects people with asthma provides reassurance that having the condition doesn’t […]

Cytokeratin 18 cell death assays as biomarkers for quantification of apoptosis and necrosis in COVID-19: a prospective, observational study


Authors: Brandon Michael Henry1, http://orcid.org/0000-0002-1211-8247Isaac Cheruiyot2, Stefanie W Benoit3,4, Fabian Sanchis-Gomar5,6, http://orcid.org/0000-0001-9523-9054Giuseppe Lippi7, Justin Benoit8 Correspondence to Dr Brandon Michael Henry, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA; Abstract Background The mechanism by which SARS-CoV-2 triggers cell damage and necrosis are yet to be fully elucidated. We sought to quantify epithelial cell death in patients with COVID-19, with an estimation of […]

Coronavirus (Covid-19)


A collection of articles and other resources on the Coronavirus (Covid-19) outbreak, including clinical reports, management guidelines, and commentary. CORONAVIRUS (COVID-19)     VACCINE RESOURCES     VACCINE FAQ https://www.nejm.org/coronavirus All Journal content related to the Covid-19 pandemic is freely available. ORIGINAL ARTICLEConvalescent Plasma for High-Risk Covid-19F.K. Korley and OthersPatients who were seen in emergency departments within 7 days after the onset of Covid-19 symptoms […]

Prevalence of Depression, Anxiety, and Stress during COVID-19 Pandemic


Authors: Ram Lakhan1 Amit Agrawal2 Manoj Sharma3 Introduction The outbreak of the third coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), also named coronavirus disease 2019 (COVID-19), has occurred more rapidly than people could have ever imagined from the experience of the past two SARS-CoV and Middle East respiratory syndrome coronavirus.1,2 To control the spread […]