Rapid detection of novel coronavirus/Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) by reverse transcription-loop-mediated isothermal amplification

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Authors: Laura E. Lamb ,Sarah N. Bartolone,Elijah Ward,Michael B. Chancellor Abstract Novel Corona virus/Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 or 2019-nCoV), and the subsequent disease caused by the virus (coronavirus disease 2019 or COVID-19), is an emerging global health concern that requires a rapid diagnostic test. Quantitative reverse transcription PCR (qRT-PCR) is currently the standard […]

Pathophysiology of acute respiratory syndrome coronavirus 2 infection: a systematic literature review to inform EULAR points to consider

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Authors: Aurélie Najm1, http://orcid.org/0000-0003-1105-5640Alessia Alunno2, Xavier Mariette3,4, http://orcid.org/0000-0001-6612-7336Benjamin Terrier5,6, http://orcid.org/0000-0003-2406-161XGabriele De Marco7,8, Jenny Emmel9, Laura Mason9, Dennis G McGonagle7,10 and http://orcid.org/0000-0002-8411-7972Pedro M Machado11,12,13 Abstract Background The SARS-CoV-2 pandemic is a global health problem. Beside the specific pathogenic effect of SARS-CoV-2, incompletely understood deleterious and aberrant host immune responses play critical roles in severe disease. Our objective was to summarise the available information on the pathophysiology […]

COVID-19 pathophysiology: A review

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Authors: COVID-19 pathophysiology: A review Koichi Yuki,⁎ Miho Fujiogi, and Sophia Koutsogiannaki Abstract In December 2019, a novel coronavirus, now named as SARS-CoV-2, caused a series of acute atypical respiratory diseases in Wuhan, Hubei Province, China. The disease caused by this virus was termed COVID-19. The virus is transmittable between humans and has caused pandemic worldwide. The […]

Acute Respiratory Distress Syndrome and COVID-19: A Scoping Review and Meta-analysis

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Authors: Mehdi Jafari-Oori 1, Fatemeh Ghasemifard 2, Abbas Ebadi 3, Leila Karimi 3, Farshid Rahimi-Bashar 4, Tannaz Jamialahmadi 5 6, Paul C Guest 7, Amir Vahedian-Azimi 8, Amirhossein Sahebkar 9 10 11 12 Abstract Acute respiratory distress syndrome (ARDS) is a fatal complication of the new severe acute respiratory syndrome coronavirus (SARS-CoV-2), which causes COVID-19 disease. This scoping review was carried out with international, peer-reviewed research studies and gray literature published up to July 2020 in […]

Worse Than the Disease? Reviewing Some Possible Unintended Consequences of the mRNA Vaccines Against COVID-19

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Authors: Stephanie Seneff1and Greg Nigh21Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge MA, 02139, USA, E-mail: seneff@csail.mit.edu 2Naturopathic Oncology, Immersion Health, Portland, OR 97214, USA ABSTRACT Operation Warp Speed brought to market in the United States two mRNA vaccines, produced by Pfizer and Moderna. Interim data suggested high efficacy for both of these vaccines, which […]

Hidden History When Vaccines go wrong…This chicken vaccine makes its virus more dangerous

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Authors: By —Nsikan Akpan The deadliest strains of viruses often take care of themselves — they flare up and then die out. This is because they are so good at destroying cells and causing illness that they ultimately kill their host before they have time to spread. But a chicken virus that represents one of […]

Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens

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Authors: Andrew F. Read ,Susan J. Baigent,Claire Powers,Lydia B. Kgosana,Luke Blackwell,Lorraine P. Smith,David A. Kennedy,Stephen W. Walkden-Brown,Venugopal K. Nair Abstract Could some vaccines drive the evolution of more virulent pathogens? Conventional wisdom is that natural selection will remove highly lethal pathogens if host death greatly reduces transmission. Vaccines that keep hosts alive but still allow transmission […]

How Likely Are Vaccinated People To Get Meaningfully Sick From Delta?

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Authors: DYLAN HOUSMAN The reality that breakthrough cases exist and being vaccinated doesn’t guarantee protection from COVID-19 has raised a new question in the minds of many Americans: just how likely is it that someone will get seriously ill from the delta variant of COVID-19 if they are vaccinated? Some clinical data suggests that vaccine […]

Covid-19 Pandemic-Scared-Vaccinated

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Authors: Authored by Emily Miller via Emily Posts The Scared Vaccinated and the Grateful Vaccinated Fauci, CNN and Aniston are spokesmen for the Scared Vaccinated. Their opposites are the Grateful Vaccinated, who have little to worry about COVID. Nine out of 10 of the vaccinated will not catch the virus. That one “breakthrough” case will […]

What Does COVID Do to Your Blood?

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Authors: Panagis Galiatsatos, M.D., M.H.S., Robert Brodsky, M.D. COVID-19 is a very complex illness. The coronavirus that causes COVID-19 attacks the body in many different ways, ranging from mild to life threatening. Different organs and tissues of the body can be affected, including the blood. Robert Brodsky, a blood specialist who directs the Division of […]