Clinical and Demographic Factors Associated With COVID-19, Severe COVID-19, and SARS-CoV-2 Infection in Adults A Secondary Cross-Protocol Analysis of 4 Randomized Clinical Trials

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Deborah A. Theodore, MD1; Angela R. Branche, MD2; Lily Zhang, PhD3; et alDaniel S. Graciaa, MD4; Madhu Choudhary, MD5; Timothy J. Hatlen, MD6; Raadhiya Osman, PhD7; Tara M. Babu, MD8; Samuel T. Robinson, PhD3; Peter B. Gilbert, PhD3,9;  Dean Follmann, PhD10;  Holly Janes, PhD3,9; James G. Kublin, MD3; Lindsey R. Baden, MD11; Paul Goepfert, MD12; Glenda E. Gray, MBBCh13,14; Beatriz Grinsztejn, MD, PhD15; Karen L. Kotloff, MD16,17; Cynthia L. Gay, MD18; Brett Leav, MD19; Jacqueline Miller, MD19; Ian Hirsch, PhD20; Jerald Sadoff, MD21; Lisa M. Dunkle, MD22; Kathleen M. Neuzil, MD17; Lawrence Corey, MD3,23; Ann R. Falsey, MD2; Hana M. El Sahly, MD24,25; Magdalena E. Sobieszczyk, MD1; Yunda Huang, PhD3,26; for the COVID-19 Prevention Network (CoVPN) JAMA Netw Open. 2023;6(7):e2323349. doi:10.1001/jamanetworkopen.2023.23349 Key Points Question  What clinical and demographic factors are associated with rates of COVID-19, severe COVID-19, and SARS-CoV-2 infection? Findings  In this secondary analysis of […]

Long-Term Sequelae of COVID-19: A Systematic Review and Meta-Analysis of One-Year Follow-Up Studies on Post-COVID Symptoms

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Authors: Qing Han 1,Bang Zheng 2,3,4,*,Luke Daines 2 and Aziz Sheikh  Pathogens 2022, 11(2), 269; https://doi.org/10.3390/pathogens11020269, Published: 19 February 2022 Emerging and/or Zoonotic Viral Infections) Abstract Emerging evidence has shown that COVID-19 survivors could suffer from persistent symptoms. However, it remains unclear whether these symptoms persist over the longer term. This study aimed to systematically synthesise evidence on post-COVID symptoms persisting for at least […]

SARS-CoV-2 vaccine breakthrough infection in the older adults: a meta-analysis and systematic review

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Xiaohui Jing, Menglin Han, Xiaoxuan Wang & Li Zhou BMC Infectious Diseases volume 23, Article number: 577 (2023) Cite this article Update published on 02 October 2023 Abstract Background Corona Virus Disease 2019 (COVID-19) mRNA vaccine effectiveness (VE) has recently declined, and reports about COVID-19 breakthrough infection have increased. We aimed to conduct a meta-analysis on population-based studies of the prevalence and incidence of severe […]

Long COVID Now Looks like a Neurological Disease, Helping Doctors to Focus Treatments

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The causes of long COVID, which disables millions, may come together in the brain and nervous system  Author: Stephani Sutherland   March 1, 2023 Tara Ghormley has always been an overachiever. She finished at the top of her class in high school, graduated summa cum laude from college and earned top honors in veterinary school. She […]

You might be able to sue the mRNA COVID vaccine manufacturers for damages

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October 22, 2023 Steve Kirsh Substack Breaking: You can now sue the mRNA COVID vaccine manufacturers for damages and the FDA is required to take the COVID vaccines off the market. Why? Adulteration. The plasmid bioactive contaminant sequences were NOT pointed out to the regulatory authorities. It’s considered adulteration. I just got off the phone […]

The real data behind the new COVID vaccines the White House is pushing

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By  Marty Makary and Tracy Beth Høeg Published Sep. 14, 2023 What if I told you one in 50 people who took a new medication had a “medically attended adverse event” and the manufacturer refused to disclose what exactly the complication was — would you take it? And what if the theoretical benefit was only transient, lasting […]

Parosmia and COVID: How Long Changes in Smell Last, Plus Treatment Options

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Christine Giordano, MD | Reviewed by Angela Dunn, MD, MPH, August 29, 2023 GoodRX Key takeaways: For some people, morning coffee smells like onions or trash. And the smell of loved ones makes them want to gag day after day. This is parosmia — a change or distortion of normal smell. And it’s one of the types of […]

Brain Injuries After COVID Vaccination

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Colleen Huber    April 12, 2023 HEALTH VIEWPOINTS, There are back door routes to the brain. COVID vaccine developers have traversed a path through those doors. And they knew they had entered the brain by November 2020, before the vaccine rollout. We have 86 billion neurons in the human brain, and each of those connects with […]

Incidence of New-Onset Hypertension Post–COVID-19: Comparison With Influenza

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Vincent Zhang, Molly Fisher,Wei Hou,Lili Zhang and Tim Q. Duong    Aug 2023 https://doi.org/10.1161/HYPERTENSIONAHA.123.21174 Hypertension. 2023;0 Abstract BACKGROUND: SARS-CoV-2 may trigger new-onset persistent hypertension. This study investigated the incidence and risk factors associated with new-onset persistent hypertension during COVID-19 hospitalization and at ≈6-month follow-up compared with influenza. METHODS: This retrospective observational study was conducted in a major academic […]

Autonomic dysfunction in ‘long COVID’: rationale, physiology and management strategies

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Melanie Dani,  Andreas Dirksen, Patricia Taraborrelli,  Miriam Torocastro, Dimitrios Panagopoulos, Richard Sutton, and Phang Boon Lim Clin Med (Lond). 2021 Jan; 21(1): e63–e67.  doi: 10.7861/clinmed.2020-0896 PMCID: PMC7850225 PMID: 33243837 ABSTRACT The SARS-CoV-2 (COVID-19) pandemic has caused unprecedented morbidity, mortality and global disruption. Following the initial surge of infections, focus shifted to managing the longer-term sequelae of illness in survivors. ‘Post-acute COVID’ (known colloquially as ‘long COVID’) is […]