Bronchiectasis: Mechanisms and Imaging Clues of Associated Common and Uncommon Diseases

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Authors: Bethany Milliron, Travis S Henry, Srihari Veeraraghavan, Brent P Little Bronchiectasis is permanent irreversible dilatation of the airways and occurs in a variety of pathologic processes. Recurrent infection and inflammation and the resulting chemical and cellular cascade lead to permanent architectural changes in the airways. Bronchiectasis can confer substantial potential morbidity, usually secondary to […]

Genomics Bioinformatic Analysis

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Authors: Patrick C Y Woo 1, Yi Huang, Susanna K P Lau, Kwok-Yung Yuen The drastic increase in the number of coronaviruses discovered and coronavirus genomes being sequenced have given us an unprecedented opportunity to perform genomics and bioinformatics analysis on this family of viruses. Coronaviruses possess the largest genomes (26.4 to 31.7 kb) among all known RNA viruses, […]

Initial study on TMPRSS2 p.Val160Met genetic variant in COVID-19 patients

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Authors: Laksmi Wulandari, Berliana Hamidah, Cennikon Pakpahan, Nevy Shinta Damayanti, Neneng Dewi Kurniati, Christophorus Oetama Adiatmaja, Monica Rizky Wigianita, Soedarsono, Dominicus Husada, Damayanti Tinduh, Cita Rosita Sigit Prakoeswa, Anang Endaryanto, Ni Nyoman Tri Puspaningsih, Yasuko Mori, Maria Inge Lusida, Kazufumi Shimizu & Delvac Oceandy  Coronavirus disease 2019 (COVID-19) is a global health problem that causes millions of deaths worldwide. The clinical manifestation of COVID-19 widely varies from asymptomatic infection to severe pneumonia […]

Genomics & Precision Medicine

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Authors: CDC Blogs Merline Feero, Marta Gwinn, and Muin J. Khoury, Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, Georgia Tracking the Scientific Literature on SARS-CoV-2 Variants Using the COVID-19 Genomics and Precision Health Knowledge Base The first reports of SARS-CoV-2, the highly infectious virus causing COVID-19, swept across […]

SEQUENCING THE GENOME OF THE VIRUS BEHIND COVID-19

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Authors: Amanda Zrebiec With software and molecular biology approaches developed in part at APL, researchers at John’s Hopkins are using handheld DNA sequencers to conduct immediate on-site genome sequencing of SARS-CoV-2—the virus that causes COVID-19. “This information allows for the tracking of the evolution of the virus. It gives clinicians a sense of where the […]

COVID-19 pandemic

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Authors: U.S. CASE COUNT: As of July 27, 2021, more than 34.5 million COVID-19 cases and more than 611,000 deaths have been reported, according to Johns Hopkins University. Among children, about 4.13 million cases and at least 349 deaths have been reported as of July 22, according to AAP data. VACCINATIONS: About 56.8% of the U.S. population has received […]

Sinus Infection and Neck Pain: Is There a Correlation?

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Authors: Olga Adereyko, MD — Primary Care Physician, General Practitioner,  People with allergies or chronic colds understand that sinus infections can be a real pain in the neck. Most cases of acute sinusitis get better on their own. Your doctor may recommend treatments to help relieve sinusitis symptoms, but acute sinusitis can cause potentially dangerous complications. […]

Long-Term Brain Disorders in Post Covid-19 Neurological Syndrome (PCNS) Patient

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Authors: Domenico Nuzzo,1,2,* Gaetano Cambula,3 Ignazio Bacile,3 Manfredi Rizzo,4 Massimo Galia,5 Paola Mangiapane,6 Pasquale Picone,1,2 Daniela Giacomazza,7 and Luca Scalisi8,9,* In the recent pandemic disease, called COVID-19, the role of neurologists and neurobiologists represents a chance to study key features of brain infection and deepen neurological manifestations of COVID-19 and other coronavirus infections. In fact, many studies suggest brain damage during infection and persistent […]

Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients

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Authors: Joanna Hellmuth 1 2, T Allen Barnett 3, Breton M Asken 4, J Daniel Kelly 5, Leonel Torres 6, Melanie L Stephens 4 7, Bryan Greenhouse 6, Jeffrey N Martin 5, Felicia C Chow 7 8, Steven G Deeks 9, Meredith Greene 10, Bruce L Miller 4 7, Wesley Annan 4 7, Timothy J Henrich 6, Michael J Peluso 9 As cases of coronavirus disease 2019 (COVID-19) mount worldwide, attention is needed on potential long-term neurologic impacts for the majority of patients who experience mild to moderate illness […]

Long-COVID syndrome-associated brain fog and chemofog: Luteolin to the rescue

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Authors: Theoharis C Theoharides 1 2 3 4 5, Christos Cholevas 5, Konstantinos Polyzoidis 5, Antonios Politis 6 COVID‐19 leads to severe respiratory problems, but also to long‐COVID syndrome associated primarily with cognitive dysfunction and fatigue. Long‐COVID syndrome symptoms, especially brain fog, are similar to those experienced by patients undertaking or following chemotherapy for cancer (chemofog or chemobrain), as well in patients with myalgic encephalomyelitis/chronic fatigue […]