Uptake of SARS-CoV-2 spike protein in human cerebrovascular cells


Authors:  Bhavana Kunkalikar Mar 24 2022 Reviewed by Danielle Ellis, B.Sc. BioRxiv A recent study posted to the bioRxiv* preprint server assessed the uptake of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in human cerebrovascular cells via the lipid raft ganglioside.   Various studies have reported the effects of coronavirus disease 2019 (COVID-19) on […]

Study evaluates mutation-induced SARS-CoV-2 spike protein fold stability


Authors: Tarun Sai Lomte Mar 24 2022 BioRxiv In a recent study posted to the bioRxiv* preprint server, researchers evaluated the stability and expression of mutations in the spike (S) protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Background The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has resulted in extensive research into S protein. […]

Pancreatic damage in COVID‐19: Why? How?


Authors: Ferhat Bacaksız, 1 Berat Ebik, 1 Nazım Ekin, 1 and Jihat Kılıc 2 Int J Clin Pract. 2021 Aug 6 : e14692.doi: 10.1111/ijcp.14692 [Epub ahead of print] PMCID:  PMC8420122PMID: 34331821 Abstract Object We aimed to evaluate the elevation of amylase and lipase enzymes in coronavirus disease 2019 (COVID‐19) patients and their relationship with the severity of COVID‐19. Method In this study, 1378 patients with COVID‐19 infection […]

Consequences of COVID-19 for the Pancreas


Authors: Urszula Abramczyk,1,*Maciej Nowaczyński,2Adam Słomczyński,2Piotr Wojnicz,2Piotr Zatyka,2 and Aleksandra Kuzan1 Int J Mol Sci. 2022 Jan; 23(2): 864.Published online 2022 Jan 13. doi: 10.3390/ijms23020864 Abstract Although coronavirus disease 2019 (COVID-19)-related major health consequences involve the lungs, a growing body of evidence indicates that COVID-19 is not inert to the pancreas either. This review presents a summary of the molecular mechanisms […]

COVID Can Cause Strange Eye and Ear Symptoms


From conjunctivitis to vertigo, coronavirus infections can affect disparate senses Authors:  Emily Sohn SCIENTIFIC AMERICAN Red eyes, ringing ears, sensitivity to light, trouble hearing: although a loss of taste and smell have become well-known sensory symptoms of COVID, accumulating research suggests that vision and hearing are also frequent targets of SARS-COV-2, the virus that causes […]

4 Ways COVID Leaves Its Mark on the Eye


Authors: Reena MukamalReviewed By Joseph T Nezgoda, MD MBASep. 14, 2021 An analysis of 121 patients dating back to the beginning of the pandemic unveils COVID’s most common effects on the eye. Share this information and remember: Widespread vaccination is key to ending the pandemic American Journal of Ophthalmology How does COVID reach the eyes? People respond in different ways […]

Is ‘COVID Eye’ a Thing?


Authors:  Susanne Medeiros;  James G Chelnis, MD Jan. 18, 2022 American Journal of Opthalmology The British press recently reported that a 9-year-old boy was nearly blinded after developing ‘Covid eye’.  He lost vision in one eye less than a week after testing positive for Covid-19. Physicians determined the boy had developed orbital cellulitis, a bacterial infection […]

Severe aplastic anemia after COVID-19 mRNA vaccination: Causality or coincidence?


Authors: Shotaro Tabata 1, Hiroki Hosoi 2, Shogo Murata 1, Satomi Takeda 1, Toshiki Mushino 1, Takashi Sonoki 1PMID: 34920343 PMCID: PMC8668346I: 10.1016/j.jaut.2021.102782 J Autoimmun. 2022 Jan; 126: 102782.Published online 2021 Dec 14. doi: 10.1016/j.jaut.2021.102782 Abstract The development of various autoimmune diseases has been reported after COVID-19 infections or vaccinations. However, no method for assessing the relationships between vaccines and the development of autoimmune diseases has been established. Aplastic anemia (AA) is […]

Bone Marrow Suppression Secondary to the COVID-19 Booster Vaccine: A Case Report


Authors: Toral Shastri 1, Navkiran Randhawa 2, Ragia Aly 3, Masood Ghouse 3 PMID: 35210894 PMCID: PMC8863340DOI: 10.2147/JBM.S350290 Abstract As of September 2021, SARS-CoV-2 booster shots became widely available in the US to ensure continued protection against the virus. A temporal relationship has been previously reported between the first or second dose of the COVID-19 vaccine and the development of thrombocytopenia. However, adverse events related […]

SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans


Authors: Jackson S. Turner, Wooseob Kim, Elizaveta Kalaidina, Charles W. Goss, Adriana M. Rauseo, Aaron J. Schmitz, Lena Hansen, Alem Haile, Michael K. Klebert, Iskra Pusic, Jane A. O’Halloran, Rachel M. Presti & Ali H. Ellebedy  Nature volume 595, pages421–425 (2021) Abstract Long-lived bone marrow plasma cells (BMPCs) are a persistent and essential source of protective antibodies1,2,3,4,5,6,7. Individuals who have recovered from COVID-19 have a substantially lower risk of reinfection with […]