Scientists blast U.S. push for Covid vaccine booster shots as premature, say data isn’t compelling

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PUBLISHED THU, AUG 19 20211:44 PM EDTUPDATED THU, AUG 19 20216:27 PM EDT Authors: Berkeley Lovelace Jr.@BERKELEYJR KEY POINTS Scientists sharply criticized the Biden administration’s push to widely distribute Covid booster shots, saying the data provided by U.S. officials wasn’t compelling. While data suggests there is a reduction in protection against mild and moderate disease, […]

Delta is surging, but is another variant on the way? Here’s what to know about lambda

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Ben Sessoms, The Charlotte Observer   The delta variant is by far the dominant strain of the coronavirus in North Carolina and the rest of the country, but experts say there are also other variants to watch. Before delta, there was alpha, beta and gamma. Now there is another, lambda, which is primarily spreading in South America. […]

US Covid-19 Breakthrough Infections-are-Uncommon Rising Considerably and D-19 Breakthrough Infections are Uncommon, Rising Considerably, and Sort of Okay

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Authors: PETER WEBER 5:20 AM The Biden administration is advising eight-month booster shots for Americans vaccinated with the Pfizer and Moderna COVID-19 vaccines because the Delta variant, which now accounts for about 98.8 percent of new U.S. infections, is a lot more contagious and the effectiveness of the vaccines appears to wane with time.  “Fortunately,” the COVID-19 vaccines are […]

Covid Vaccines Are Less Effective Against Delta, Large Study Finds Naomi Kresge Bookmark August 19 2021, 4:31 AM

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Authors: Naomi Kresge Copyright © BloombergQuintCopyright © Covid-19 vaccines are less effective against the delta variant, according to results in the U.K. from one of the largest real-world studies into the efficacy of the shots. Pfizer Inc. and BioNTech SE’s messenger RNA vaccine lost effectiveness in the first 90 days after full vaccination, though that […]

Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19) a randomized, double-blind, placebo-controlled trial

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Authors: Julio Vallejos, Rodrigo Zoni, María Gabriela Aguirre  Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has changed our lives. The scientific community has been investigating re-purposed treatments to prevent disease progression in coronavirus disease (COVID-19) patients. Objective To determine whether ivermectin treatment can prevent hospitalization in individuals with early COVID-19. Design, setting and participants: A […]

Post-acute COVID-19 syndrome

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Authors: Ani Nalbandian, Kartik Sehgal, Elaine Y. Wan Nature Medicine volume 27, pages601–615 (2021) Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in global healthcare crises and strained health resources. As the population of patients recovering from COVID-19 grows, it is paramount to establish an understanding of […]

Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19

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Authors: JACC State-of-the-Art ReviewAzita H. Talasaz, PharmD,a,bParham Sadeghipour, MD,cHessam Kakavand, PharmD,a,bMaryam Aghakouchakzadeh, PharmD,aElaheh Kordzadeh-Kermani, PharmD,aBenjamin W. Van Tassell, PharmD,d,eAzin Gheymati, PharmD,aHamid Ariannejad, MD,bSeyed Hossein Hosseini, PharmD,aSepehr Jamalkhani,cMichelle Sholzberg, MDCM, MSc,f,gManuel Monreal, MD, PhD,hDavid Jimenez, MD, PhD,iGregory Piazza, MD, MS,jSahil A. Parikh, MD,k,lAjay J. Kirtane, MD, SM,k,lJohn W. Eikelboom, MBBS,mJean M. Connors, MD,nBeverley J. Hunt, MD,oStavros V. […]

COVID-19 vaccines and thrombosis with thrombocytopenia syndrome

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Authors: Chih-Cheng Lai 1, Wen-Chien Ko 2, Chih-Jung Chen 3, Po-Yen Chen 4, Yhu-Chering Huang 3, Ping-Ing Lee 5, Po-Ren Hsueh 6 7 Abstract Introduction: To combat COVID-19, scientists all over the world have expedited the process of vaccine development. Although interim analyses of clinical trials have demonstrated the efficacy and safety of COVID-19 vaccines, a serious but rare adverse event, thrombosis with thrombocytopenia syndrome (TTS), has been reported following […]

Anticoagulation in COVID-19: current concepts and controversies

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Authors: http://orcid.org/0000-0002-3809-8926Atanu Chandra1, 6289Uddalak Chakraborty2, Shrestha Ghosh1, Sugata Dasgupta3 Abstract Rising incidence of thromboembolism secondary to COVID-19 has become a global concern, with several surveys reporting increased mortality rates. Thrombogenic potential of the SARS-CoV-2 virus has been hypothesised to originate from its ability to produce an exaggerated inflammatory response leading to endothelial dysfunction. Anticoagulants have remained the primary […]

Clinical Outcomes for Patients With Anosmia 1 Year After COVID-19 Diagnosis

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Authors: Marion Renaud, MD1; Claire Thibault, MD1; Floriane Le Normand, MD1; et al Introduction Since the pandemic was declared in early 2020, COVID-19–related anosmia quickly emerged as a telltale sign of infection.1,2 However, the time course and reversibility of COVID-19–related olfactory disorders, which may persist and negatively affect patients’ lives, require further study. To clarify the clinical course and prognosis, we followed a cohort of […]