Molecular architecture of coronavirus double-membrane vesicle pore complex

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Yixin Huang, Tongyun Wang, Lijie Zhong, et. al., Nature  Abstract Coronaviruses remodel the intracellular host membranes during replication, forming double-membrane vesicles (DMVs) to accommodate viral RNA synthesis and modifications1,2. SARS-CoV-2 non-structural protein 3 (nsp3) and nsp4 are the minimal viral components required to induce DMV formation and to form a double-membrane-spanning pore, essential for the transport of newly […]

Risks of digestive diseases in long COVID: evidence from a population-based cohort study

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Yuying Ma, Lijun Zhang, Rui Wei, et. al, BMC Medicine volume 22, Article number: 14 (2024) Cite this article Abstract Background In the post-pandemic era, a wide range of COVID-19 sequelae is of growing health concern. However, the risks of digestive diseases in long COVID have not been comprehensively understood. To investigate the long-term risk of digestive diseases among COVID patients. Methods In this […]

Sleep and Long COVID—A Review and Exploration of Sleep Disturbances in Post Acute Sequelae of SARS-COV-2 (PASC) and Therapeutic Possibilities

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Volume 10, pages 169–180, (2024), Elliott K Lee & R. Robert Auger  Abstract Purpose of Review Post Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2), also known as PASC, and frequently referred to as “long-COVID,” is estimated to afflict over 65 million people worldwide. Sleep disturbances and fatigue are some of the most frequently cited PASC symptoms, and […]

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches

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Roxana Gheorghita1,2Iuliana Soldanescu3Andrei Lobiuc2 , et. al., Front. Immunol., 03 March 2024, Sec. Viral Immunology, Volume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1344086 The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been defined as the greatest global health and socioeconomic crisis of modern times. While most people recover after being infected with the virus, a significant […]

Inflammation: The Body’s ‘Fire’ Burns Threats, But Things Go Wrong When It Smolders

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Authored by Flora Zhao via The Epoch Times Many people experience chronic inflammation without even knowing it, Arch G. Mainous III, a professor at the University of Florida (UF) College of Medicine, told The Epoch Times. A large-scale study published in Frontiers in Medicine in 2024 showed that among adults in the United States, almost 35 percent had […]

Pathophysiological, immunological, and inflammatory features of long COVID

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Karen Bohmwald1,2†Benjamín Diethelm-Varela1†Linmar Rodríguez-Guilarte1 , et. al., Front. Immunol., 27 February 2024, Sec. Viral Immunology, Volume 15 – 2024 | https://doi.org/10.3389/fimmu.2024.1341600 The COVID-19 pandemic continues to cause severe global disruption, resulting in significant excess mortality, overwhelming healthcare systems, and imposing substantial social and economic burdens on nations. While most of the attention and therapeutic efforts have […]

First-Of-Its-Kind Study Explains Why Some People Don’t Get COVID-19

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JUN 20, 2024 – Authored by Marina Zhang via The Epoch Times  Researchers have discovered why some people remain uninfected by the COVID-19 virus—even after their nasal cavities are exposed to it. According to a recent study, these people have faster and more subtle immune responses than those who develop symptomatic COVID-19. “These findings shed […]

Panic!!! CDC Says “Very High” COVID-19 Levels Reported In 32 States

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Authored by Jack Phillips via The Epoch Times, 9/19/2024 The U.S. Centers for Disease Control and Prevention (CDC) said that COVID-19 levels across the United States are currently “very high” in more than half of states, with Omicron variants KP.3 and KP.3.1.1 accounting for about half of all cases. Citing wastewater data as of Aug. 15, the […]

Appeals Court Revives Case Against COVID-19 Vaccine Requirement

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Authored by Zachary Stieber via The Epoch Times  A U.S. appeals court on June 18 revived a case against a COVID-19 vaccine mandate issued by a city in Washington state under a proclamation from state officials. Firefighters who applied for exemptions to the Spokane mandate “plausibly assert that the individual city defendants applied the proclamation […]

Superior Mesenteric Artery Thrombosis in COVID-19-Positive Patients: A Rare Coincidence

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Rushabh Parekh • Virendra Athavale • Saili Kelshikar, : June 11, 2024, DOI: 10.7759/cureus.62136  Abstract Since the start of the SARS-CoV-2 pandemic, which is otherwise known as the worldwide coronavirus disease, 2019, has had a well-established pro-thrombotic character. Patients often first exhibit respiratory symptoms, and those whose severity increases eventually develop acute hypoxic respiratory failure. The systemic hypercoagulable condition and arterial/venous […]