Authors: Bhanu Kanth Manne (University of Utah, United States) Frederik Denorme (Molecular Medicine Program, University of Utah, United States), Elizabeth Middleton (University of Utah, United States), Irina Portier (University of Utah, United States) Jesse Rowley (University of Utah, United, States) Chris Stubben (University of Utah, United States) Aaron Petrey (University of Utah, United States) Neal […]
Authors: Si Zhang 1, Yangyang Liu 2, Xiaofang Wang 2, Li Yang 3, Haishan Li 4, Yuyan Wang 5, Mengduan Liu 2, Xiaoyan Zhao 2, Youhua Xie 5, Yan Yang 6, Shenghui Zhang 7, Zhichao Fan 8, Jianzeng Dong 2, Zhenghong Yuan 5, Zhongren Ding 2, Yi Zhang 9, Liang Hu 10 Abstract Background: Critically ill patients diagnosed with COVID-19 may develop a pro-thrombotic state that places them at a dramatically increased lethal risk. Although platelet activation is critical for thrombosis and is responsible for the thrombotic events and […]
Authors: Geoffrey D Wool 1, Jonathan L Miller 2 Abstract Coronavirus disease 2019 (COVID-19) causes a spectrum of disease; some patients develop a severe proinflammatory state which can be associated with a unique coagulopathy and procoagulant endothelial phenotype. Initially, COVID-19 infection produces a prominent elevation of fibrinogen and D-dimer/fibrin(ogen) degradation products. This is associated with systemic hypercoagulability and […]
Authors: Michael Repajic,a Xue Lei Lai,a Prissilla Xu,b and Antonio Liua,∗ Abstract Objective To report a patient with history of recurrent Bell’s Palsy who developed Bell’s Palsy 36 h after the administration of the second dose of the Pfizer-BioNTech COVID-19 vaccine. Case The patient is a 57-year-old female with past medical history of 3 episodes of Bell’s Palsy. She responded […]
Authors: 24 FEB 2021 The Lancet Ozonoff et al. There is a possible increased risk of developing Bell’s palsy in COVID-19 mRNA vaccine recipients, but the rate was extremely low (7 cases in 40,000 participants vaccinated), and was not statistically significantly different than the rate seen in the placebo recipients. This condition usually self-resolves. Preventing the risk […]
Authors: Giuseppe Colella,1Massimiliano Orlandi,2 and Nicola Cirillo1,3 Currently two Coronavirus Disease 2019 (COVID-19) vaccines have been granted emergency use and marketing authorization by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) [1, 2]. Initial efficacy and safety data for both BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) vaccines have been published [3, 4]. To the best […]
Authors: Narayanappa Amruta,a Wesley H. Chastain,a Meshi Paz,a Rebecca J. Solch,b Isabel C. Murray-Brown,a Jaime B. Befeler,a Timothy E. Gressett,a Michele T. Longo,b,c Elizabeth B. Engler-Chiurazzi,a,c and Gregory Bixa,b,c,* Abstract SARS-CoV-2 is a novel coronavirus that severely affects the respiratory system, is the cause of the COVID-19 pandemic, and is projected to result in the deaths of 2 million people worldwide. Recent reports suggest that […]
Authors: Mary Van Beusekom | News Writer | CIDRAP News | Jul 30, 2021 New studies show an association between COVID-19 and cognitive impairment in older patients, with one reporting memory problems and worse physical health 8 months after diagnosis and others finding cognitive decline and accelerated Alzheimer’s disease symptoms as long as 6 months after infection. […]
Authors: Anthony L. Komaroff, MD, reviewing Yang AC et al. Nature 2021 Jul Marshall M. Nature 2021 Jul In deceased COVID-19 patients, gene expression in the choroid plexus was altered. People infected with SARS-CoV-2 can develop a wide variety of neurological conditions: Endothelial dysfunction can lead to ischemic and hemorrhagic strokes, even in young adults. Demyelinating diseases occur. Autoantibodies that […]
Authors: Laura Pellegrini 1, Anna Albecka 1, Donna L Mallery 1, Max J Kellner 1, David Paul 1, Andrew P Carter 1, Leo C James 1, Madeline A Lancaster 2 Abstract Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, leads to respiratory symptoms that can be fatal. However, neurological symptoms have also been observed in some patients. The cause of these complications is […]