Use of DAMPs and SAMPs as Therapeutic Targets or Therapeutics: A Note of Caution


2020 Jun;24(3):251-262. doi: 10.1007/s40291-020-00460-z. Walter Gottlieb Land 1 2 PMID: 32248387 PMCID: PMC7127836 DOI: 10.1007/s40291-020-00460-z Free PMC article Abstract This opinion article discusses the increasing attention paid to the role of activating damage-associated molecular patterns (DAMPs)…[...]

Role of DAMPs in respiratory virus-induced acute respiratory distress syndrome—with a preliminary reference to SARS-CoV-2 pneumonia


Review Article; Published: 17 June 2021 Authors: Walter Gottlieb Land Genes & Immunity volume 22, pages141–160 (2021 )Cite this article Abstract When surveying the current literature on COVID-19, the “cytokine storm” is considered to be…[...]

Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients


Authors: Joram Huckriede, Sara Bülow Anderberg, Albert Morales, Femke de Vries, Michael Hultström, Anders Bergqvist, José T. Ortiz-Pérez, Jan Willem Sels, Kanin Wichapong, Miklos Lipcsey, Marcel van de Poll, Anders Larsson, Tomas Luther, Chris Reutelingsperger, Pablo Garcia de Frutos, Robert Frithiof & Gerry A. F. Nicolaes  Scientific…[...]

Vaccines show declining effectiveness against infection overall but strong protection against hospitalization amid delta variant


Authors: Ben Guarino  2 hrs agoLike6 Comments|51 Three studies published Wednesday by the Centers for Disease Control and Prevention show that protection against the coronavirus from vaccines declined in the midsummer…[...]

Neurologic Manifestations Associations of COVID-19


High-quality epidemiologic data is still urgently needed to better understand neurologic effects of COVID-19. Authors: Shraddha Mainali, MD; and Marin Darsie, MD VIEW/PRINT PDF Severe acute respiratory syndrome coronavirus 2…[...]

Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms


Authors: Amy D. Proal1 and Michael B. VanElzakker1,2* The novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset…[...]

Potential mechanisms of cerebrovascular diseases in COVID-19 patients


Authors: Manxue Lou 1, Dezhi Yuan 2 3, Shengtao Liao 4, Linyan Tong 1, Jinfang Li 5Affiliations expand Abstract Since the outbreak of coronavirus disease 2019 (COVID-19) in 2019, it is gaining worldwide attention at the moment. Apart from respiratory manifestations,…[...]

The Impact of the Covid 19 Pandemic on Cerebrovascular Disease: CORD-Papers-2021-06-28


Abstract:            Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a systemic disease that affects nearly all organ systems through infection and subsequent dysregulation of the vascular endothelium. One of the…[...]

C-Reactive Protein Level May Predict the Risk of COVID-19 Aggravation


Authors: Guyi Wang 1, Chenfang Wu 1, Quan Zhang 2, Fang Wu 3, Bo Yu 1, Jianlei Lv 2, Yiming Li 4, Tiao Li 5, Siye Zhang 1, Chao Wu 6 7 8, Guobao Wu 1, Yanjun Zhong 1Affiliations expand Abstract Background: Clinical findings indicated that a fraction of coronavirus disease 2019 (COVID-19) patients diagnosed as mild…[...]