SARS-CoV-2-Specific Memory T Lymphocytes From COVID-19 Convalescent Donors: Identification, Biobanking, and Large-Scale Production for Adoptive Cell Therapy

Posted on | Posted on John Murphy | Leave a Comment on SARS-CoV-2-Specific Memory T Lymphocytes From COVID-19 Convalescent Donors: Identification, Biobanking, and Large-Scale Production for Adoptive Cell Therapy

Authors: C. Ferreras1†, B. Pascual-Miguel1†, C. Mestre-Durán1, A. Navarro-Zapata1, L. Clares-Villa1, C. Martín-Cortázar1, R. De Paz2, A. Marcos2, J. L. Vicario3, A. Balas3, F. García-Sánchez3, C. Eguizabal4,5, C. Solano6, M. Mora-Rillo7, B. Soria8,9 and A. Pérez-Martínez1,10,11* Syndrome coronavirus 2 (SARS-CoV-2) pandemic is causing a second outbreak…[...]

COVID‐19: immunopathology, pathophysiological mechanisms, and treatment options

Posted on | Posted on John Murphy | Leave a Comment on COVID‐19: immunopathology, pathophysiological mechanisms, and treatment options

Authors: Larissa E van Eijk, 1 , † Mathijs Binkhorst, 2 , † Arno R Bourgonje, 3 , ‡ Annette K Offringa, 4 , ‡ Douwe J Mulder, 5 Eelke M Bos, 6 Nikola Kolundzic, 7 , 8 Amaal E Abdulle, 5 Peter HJ van der Voort, 9 Marcel GM Olde Rikkert, 10 Johannes G…[...]

The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets

Posted on | Posted on John Murphy | Leave a Comment on The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets

Authors: Williamson, Jack A. Hassard, Ecco Staller, Brian Hanley, Michael Osborn, Mauro Giacca, Andrew D. Davidson, David A. Matthews & Wendy S. Barclay SARS-CoV-2 entry requires sequential cleavage of the spike glycoprotein at the S1/S2 and the S2ʹ cleavage…[...]

Dr. Charles Hoffe issues Vaccine warning… Deep dive on endothelial damage to blood vessels…

Posted on | Posted on John Murphy | Leave a Comment on Dr. Charles Hoffe issues Vaccine warning… Deep dive on endothelial damage to blood vessels…

Author: Dr. Charles Hoffe in a Coronavirus, that spike protein becomes part of the viral capsule. In other words, the cell wall around the virus, called the viral capsule. But…[...]

Eye scan could determine whether COVID patients will be ‘long haulers’

Posted on | Posted on John Murphy | Leave a Comment on Eye scan could determine whether COVID patients will be ‘long haulers’

Authors: by Study Finds Long COVID” continues to confound doctors as patients still struggle with debilitating symptoms months after first being infection. A new study now suggests that COVID patients…[...]

Never ignore extremely elevated D-dimer levels: they are specific for serious illness

Posted on | Posted on John Murphy | Leave a Comment on Never ignore extremely elevated D-dimer levels: they are specific for serious illness

Authors: T Schutte 1, A Thijs, Y M Smulders D-dimer is routinely measured as part of the clinical diagnosis algorithms for venous thromboembolism (VTE). In these algorithms, low D- dimer cut-off values are…[...]