Comorbidity and its Impact on Patients with COVID-19


Authors: Adekunle Sanyaolu 1, Chuku Okorie 2, Aleksandra Marinkovic 3, Risha Patidar 3, Kokab Younis 4, Priyank Desai 5, Zaheeda Hosein 6, Inderbir Padda 7, Jasmine Mangat 6, Mohsin Altaf 8 Abstract A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in Wuhan, China, in…[...]

Comparative study of hospitalized children with acute respiratory distress syndrome caused by SARS-CoV-2 and influenza virus


Authors: Xinghua Liu, Wei Li, Bo Zhang, Yan Guo, Zhao Hu, Cao Peng, Xiao Lei, Qunying Luo, Qiong hang, Wei Deng, Juanjuan Wang, Jianqiao Tang, Yunqiao Li & Jianying Chen BMC Infectious Diseases volume 21, Article number: 412 (2021)  Abstract Background Since the outbreak of coronavirus disease 2019 in December…[...]

COVID-19: an update and cardiac involvement


Authors: Nizar R. Alwaqfi & Khalid S. Ibrahim  Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through angiotensin converting enzyme 2 receptors, leading to coronavirus disease (COVID-19)-related pneumonia, and…[...]

Virology, transmission, and pathogenesis of SARS-CoV-2


Authors: Muge Cevik, clinical lecturer1 2,  Krutika Kuppalli, assistant professor3,  Jason Kindrachuk, assistant professor of virology4,  Malik Peiris, professor of virology5 What you need to know SARS-CoV-2 is genetically similar to…[...]

Severe covid-19 pneumonia: pathogenesis and clinical management


Authors: Amy H Attaway, assistant professor of medicine, associate director, COPD center1,  Rachel G Scheraga, assistant professor of medicine1 2,  Adarsh Bhimraj, head, section of neurological infections; staff, infectious diseases1,  Michelle…[...]

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents A Systematic Review


Authors: Riccardo Castagnoli, MD1,2; Martina Votto, MD1,2; Amelia Licari, MD1,2; et al Key Points Question  What are the clinical features of pediatric patients with coronavirus disease 2019 (COVID-19)? Findings  In this systematic review of 18 studies with 1065 participants, most pediatric…[...]

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19) – anatomic pathology perspective on current knowledge


Authors: Sambit K. Mohanty, Abhishek Satapathy, Machita M. Naidu, Sanjay Mukhopadhyay, Shivani Sharma, Lisa M. Barton, Edana Stroberg, Eric J. Duval, Dinesh Pradhan, Alexandar Tzankov & Anil V. Parwani  Abstract Background The world is currently witnessing a major devastating pandemic of…[...]

COVID-19: Current understanding of its Pathophysiology, Clinical presentation and Treatment


Authors: Anant Parasher Abstract Background The severe acute respiratory syndrome (SARS) coronavirus-2 is a novel coronavirus belonging to the family Coronaviridae and is now known to be responsible for the outbreak…[...]

The role of extracorporeal membrane oxygenation in critically ill patients with COVID-19: a narrative review


Authors: Shiqian Huang, Shuai Zhao, Huilin Luo, Zhouyang Wu, Jing Wu, Haifa Xia & Xiangdong Chen BMC Pulmonary Medicine volume 21, Article number: 116 (2021) Abstract Extracorporeal life support treatments such as extracorporeal membrane oxygenation (ECMO) have been recommended for the treatment of…[...]