Hyperglycemia in Acute COVID-19 is Characterized by Adipose Tissue Dysfunction and Insulin Resistance


Authors: Reiterer M, Rajan M, Gómez-Banoy N, Lau JD, Gomez-Escobar LG, Gilani A, Alvarez-Mulett S, Sholle ET, Chandar V, Bram Y, Hoffman K, Rubio-Navarro A, Uhl S, Shukla AP, Goyal P, tenOever BR, Alonso LC, Schwartz RE, Schenck EJ, Safford MM Abstract  COVID-19 has proven to be a metabolic…[...]

Biden to require nursing homes get staff vaccinated or lose federal funds


Authors: By Jeremy Diamond, CNN Updated 2:38 PM ET, Wed August 18, 2021 (CNN)The Biden administration will direct all nursing homes to require their staff be vaccinated against Covid-19 in order to continue receiving Medicare…[...]

Blood molecular markers associated with COVID-19 immunopathology and multi-organ damage


Authors: Yan-Mei ChenYuanting ZhengYing YuYunzhi WangQingxia HuangFeng QianLei SunZhi-Gang SongZiyin ChenJinwen FengYanpeng AnJingcheng YangZhenqiang SuShanyue SunFahui DaiQinsheng ChenQinwei LuPengcheng LiYun LingZhong YangHuiru TangLeming ShiLi JinEdward C HolmesChen DingTong-Yu ZhuYong-Zhen Zhang…[...]

Severe COVID-19: what have we learned with the immunopathogenesis?


Authors: Bruno Bordallo,  Mozart Bellas, Arthur Fernandes Cortez, Matheus Vieira & Marcelo Pinheiro  Advances in Rheumatology volume 60, Article number: 50 (2020) Cite this article Abstract The COVID-19 outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become…[...]

Circulating mitochondrial DNA is an early indicator of severe illness and mortality from COVID-19


Authors: Davide Scozzi,1Marlene Cano,2Lina Ma,2Dequan Zhou,1Ji Hong Zhu,1Jane A. O’Halloran,3Charles Goss,4Adriana M. Rauseo,3Zhiyi Liu,1Sanjaya K. Sahu,2Valentina Peritore,5Monica Rocco,6Alberto Ricci,7Rachele Amodeo,8Laura Aimati,8Mohsen Ibrahim,1,5Ramsey Hachem,2Daniel Kreisel,1Philip A. Mudd,9Hrishikesh S. Kulkarni,2,10 and Andrew E. Gelman1,11…[...]

Pathophysiology of COVID-19:


Mechanisms Underlying Disease Severity and Progression Authors: Mary Kathryn Bohn,1,2, Alexandra Hall,1 Lusia Sepiashvili,1,2, Benjamin Jung,1,2 Shannon, Steele,1 and Khosrow Adeli1,2,3 The global epidemiology of coronavirus disease 2019 (COVID-19) suggests…[...]

Use of DAMPs and SAMPs as Therapeutic Targets or Therapeutics: A Note of Caution


2020 Jun;24(3):251-262. doi: 10.1007/s40291-020-00460-z. Walter Gottlieb Land 1 2 PMID: 32248387 PMCID: PMC7127836 DOI: 10.1007/s40291-020-00460-z Free PMC article Abstract This opinion article discusses the increasing attention paid to the role of activating damage-associated molecular patterns (DAMPs)…[...]