Clinical Outcomes for Patients With Anosmia 1 Year After COVID-19 Diagnosis


Authors: Marion Renaud, MD1; Claire Thibault, MD1; Floriane Le Normand, MD1; et al Introduction Since the pandemic was declared in early 2020, COVID-19–related anosmia quickly emerged as a telltale sign of infection.1,2 However, the time course and reversibility of COVID-19–related olfactory disorders, which may persist and negatively affect patients’ lives, require further study. To clarify the clinical course and prognosis, we followed a cohort of […]

Anosmia and dysgeusia in SARS-CoV-2 infection: incidence and effects on COVID-19 severity and mortality, and the possible pathobiology mechanisms – a systematic review and meta-analysis


Authors: Endang Mutiawati, Conceptualization, Data Curation, Resources, Validation, Writing – Original Draft Preparation, Writing – Review & Editing,a,1,2Marhami Fahriani, Conceptualization, Data Curation, Investigation, Methodology, Validation, Writing – Original Draft Preparation, Writing – Review & Editing,3Sukamto S. Mamada, Data Curation, Investigation, Validation, Writing – Review & Editing,4Jonny Karunia Fajar, Conceptualization, Formal Analysis, Investigation, Methodology, Writing – Review & Editing,3,5Andri Frediansyah, Data Curation, Investigation, Writing – Original Draft Preparation, Writing – Review & Editing,6Helnida Anggun Maliga, Data Curation, Investigation, Validation, Writing – Review & Editing,7Muhammad Ilmawan, Data Curation, Investigation, Validation, Writing […]

Parosmia post COVID-19: an unpleasant manifestation of long COVID syndrome


As we begin to slowly unravel the mystery hidden behind the current pandemic, novel clinical manifestations are emerging ceaselessly following SARS-CoV-2. Olfactory dysfunction, which has become one of the sought-after clinical features of COVID-19, has been associated with less severe disease manifestation.1 Yet, the previously deemed ‘fortunate’ patients with olfactory dysfunction who successfully recovered from […]

Overweight/obesity as the potentially most important lifestyle factor associated with signs of pneumonia in COVID-19


Authors: Vanessa Sacco ,Barbara Rauch ,Christina Gar,Stefanie Haschka,Anne L. Potzel,Stefanie Kern-Matschilles,Friederike Banning,Irina Benz,Mandy Meisel,Jochen Seissler,Andreas Lechner  Published: November 18, 2020 Abstract Objective The occurrence of pneumonia separates severe cases of COVID-19 from the majority of cases with mild disease. However, the factors determining whether or not pneumonia develops remain to be fully uncovered. We therefore explored the […]

Hyperglycemia in Acute COVID-19 is Characterized by Adipose Tissue Dysfunction and Insulin Resistance


Authors: Reiterer M, Rajan M, Gómez-Banoy N, Lau JD, Gomez-Escobar LG, Gilani A, Alvarez-Mulett S, Sholle ET, Chandar V, Bram Y, Hoffman K, Rubio-Navarro A, Uhl S, Shukla AP, Goyal P, tenOever BR, Alonso LC, Schwartz RE, Schenck EJ, Safford MM Abstract  COVID-19 has proven to be a metabolic disease resulting in adverse outcomes in individuals with diabetes or obesity. Patients infected with SARS-CoV-2 and hyperglycemia suffer from longer hospital stays, higher risk of […]

Those Anti-Covid Plastic Barriers Probably Don’t Help and May Make Things Worse


Authors: August 19, 2021in News Covid precautions have turned many parts of our world into a giant salad bar, with plastic barriers separating sales clerks from shoppers, dividing customers at nail salons and shielding students from their classmates. Intuition tells us a plastic shield would be protective against germs. But scientists who study aerosols, air flow […]

CDC Data Shows ‘Worrying Drop’ in Vaccine Efficacy over Time


Authors: HANNAH BLEAU18 Aug 2021 Data from the Centers for Disease Control and Prevention (CDC) has demonstrated what has been described as a “worrying drop” in coronavirus vaccine efficacy over time, leading to the Biden administration’s conclusion to push vaccine booster shots. “This is what moved the needle,” a senior Biden administration official said to Politico of the CDC’s […]

Biden to require nursing homes get staff vaccinated or lose federal funds


Authors: By Jeremy Diamond, CNN Updated 2:38 PM ET, Wed August 18, 2021 (CNN)The Biden administration will direct all nursing homes to require their staff be vaccinated against Covid-19 in order to continue receiving Medicare and Medicaid funding, administration officials told CNN. President Joe Biden will announce Wednesday afternoon that he is directing the Department of Health and Human Services […]

Blood molecular markers associated with COVID-19 immunopathology and multi-organ damage


Authors: Yan-Mei ChenYuanting ZhengYing YuYunzhi WangQingxia HuangFeng QianLei SunZhi-Gang SongZiyin ChenJinwen FengYanpeng AnJingcheng YangZhenqiang SuShanyue SunFahui DaiQinsheng ChenQinwei LuPengcheng LiYun LingZhong YangHuiru TangLeming ShiLi JinEdward C HolmesChen DingTong-Yu ZhuYong-Zhen Zhang Abstract COVID-19 is characterized by dysregulated immune responses, metabolic dysfunction and adverse effects on the function of multiple organs. To understand host responses to COVID-19 […]

Severe COVID-19: what have we learned with the immunopathogenesis?


Authors: Bruno Bordallo,  Mozart Bellas, Arthur Fernandes Cortez, Matheus Vieira & Marcelo Pinheiro  Advances in Rheumatology volume 60, Article number: 50 (2020) Cite this article Abstract The COVID-19 outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global major concern. In this review, we addressed a theoretical model on immunopathogenesis associated with severe COVID-19, based on the current literature of SARS-CoV-2 […]