Authors: Johns Hopkins Dr. Marty Makary The news about the U.S. Covid pandemic is even better than you’ve heard. Some 80% to 85% of American adults are immune to the virus: More than 64% have received at least one vaccine dose and, of those who haven’t, roughly half have natural immunity from prior infection. There’s […]
Authors: Keshav K. Singh,* Gyaneshwer Chaubey,* Jake Y. Chen, and Prashanth Suravajhala Because of the ongoing pandemic around the world, the mechanisms underlying the SARS-CoV-2-induced COVID-19 are subject to intense investigation. Based on available data for the SARS-CoV-1 virus, we suggest how CoV-2 localization of RNA transcripts in mitochondria hijacks the host cell’s mitochondrial function to viral advantage. […]
Authors: Carolyn Crist A large number of people who contract the coronavirus don’t fully recover in a few weeks, and many of them are experiencing chronic fatigue. More than a third of those who have tested positive for COVID-19 and have symptoms don’t feel like they’re back to normal, even weeks later, according to a new […]
Authors: Yujun Tang,† Jiajia Liu,† Dingyi Zhang, Zhenghao Xu, Jinjun Ji,* and Chengping Wen* Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes coronavirus disease 2019 (COVID-19). As of 25 May 2020, the outbreak of COVID-19 has caused 347,192 deaths around the world. The current evidence showed that severely ill patients tend to have a high concentration of […]
Authors: Víctor J Costela-Ruiz 1, Rebeca Illescas-Montes 1, Jose M Puerta-Puerta 2, Concepción Ruiz 3, Lucia Melguizo-Rodríguez 1 COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of physiopathological mechanisms that mobilize a wide variety of biomolecules, mainly immunological in nature. In the most severe cases, the prognosis can be markedly worsened by the hyperproduction of mainly proinflammatory cytokines, such as […]
Authors: Mehmet Soy 1, Gökhan Keser 2, Pamir Atagündüz 3, Fehmi Tabak 4, Işık Atagündüz 5, Servet Kayhan COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes only mild symptoms in the majority of the cases, while immunologic complications such as macrophage activation syndrome also known as secondary hemophagocytic lymphohistiocytosis, resulting in cytokine storm syndrome and acute respiratory distress syndrome, may […]
Authors: If you’re taking a type of medication known as tumor necrosis factor inhibitors, also called anti-TNF or TNFis, you may be wondering how these drugs could impact your chances of contracting COVID-19, or having more severe complications from it. After all, the common cold or other upper respiratory tract infections can be more common […]
Authors: Joanna Hellmuth 1 2, T Allen Barnett 3, Breton M Asken 4, J Daniel Kelly 5, Leonel Torres 6, Melanie L Stephens 4 7, Bryan Greenhouse 6, Jeffrey N Martin 5, Felicia C Chow 7 8, Steven G Deeks 9, Meredith Greene 10, Bruce L Miller 4 7, Wesley Annan 4 7, Timothy J Henrich 6, Michael J Peluso 9 As cases of coronavirus disease 2019 (COVID-19) mount worldwide, attention is needed on potential long-term neurologic impacts for the majority of patients who experience mild to moderate illness […]
Authors: Meghna Rao The Centers for Disease Control and Prevention (CDC) recommends that individuals with autoimmune diseases and those with weakened immune systems receive the COVID-19 vaccines; however, no solid data are currently available regarding their safety specifically in populations with autoimmune conditions.1 On the other hand, researchers have indicated that patients with autoimmune and inflammatory […]
Authors: Aakriti Gupta, Mahesh V. Madhavan, […]Donald W. Landry Although COVID-19 is most well known for causing substantial respiratory pathology, it can also result in several extrapulmonary manifestations. These conditions include thrombotic complications, myocardial dysfunction and arrhythmia, acute coronary syndromes, acute kidney injury, gastrointestinal symptoms, hepatocellular injury, hyperglycemia and ketosis, neurologic illnesses, ocular symptoms, and dermatologic complications. […]
