What Is a Cytokine Storm? Doctors Explain How Some COVID-19 Patients’ Immune Systems Turn Deadly


Authors: Sarah Bradley The news cycle is heavily saturated with stress-inducing information about COVID-19, but one of the most worrying aspects so far has been the huge disparity in the way the novel…[...]

Cytokine Storm in COVID-19—Immunopathological Mechanisms, Clinical Considerations, and Therapeutic Approaches: The REPROGRAM Consortium Position Paper


Authors: Sonu Bhaskar,1,2,3,* Akansha Sinha,1,4 Maciej Banach,1,5,6,7 Shikha Mittoo,1,8 Robert Weissert,1,9 Joseph S. Kass,1,10 Santhosh Rajagopal,1,11 Anupama R. Pai,1,12 and Shelby Kutty1,13,14 Cytokine storm is an acute hyperinflammatory response that may be responsible for critical illness in many conditions…[...]

COVID-19 cytokine storm: The anger of inflammation


Authors: Mehdi Mahmudpour 1, Jamshid Roozbeh 2, Mohsen Keshavarz 1, Shokrollah Farrokhi 3, Iraj Nabipour 4 Patients with COVID-19 who require ICU admission might have the cytokine storm. It is a state of out-of-control release of a variety of…[...]

Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies


Authors: Yujun Tang,† Jiajia Liu,† Dingyi Zhang, Zhenghao Xu, Jinjun Ji,* and Chengping Wen* Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes coronavirus disease 2019 (COVID-19). As of 25 May 2020, the…[...]

SARS-CoV-2 infection: The role of cytokines in COVID-19 disease


Authors: Víctor J Costela-Ruiz 1, Rebeca Illescas-Montes 1, Jose M Puerta-Puerta 2, Concepción Ruiz 3, Lucia Melguizo-Rodríguez 1 COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of physiopathological mechanisms that mobilize a wide variety of…[...]