Authors: Zhen W Mei, Xander M R van Wijk, Huy P Pham, Maximo J Marin The Journal of Applied Laboratory Medicine, Volume 6, Issue 5, September 2021, Pages 1305–1315, https://doi.org/10.1093/jalm/jfab042Published: 13 June 2021 Abstract […]
Elevated P-Selectin in Severe Covid-19: Considerations for Therapeutic Options
Authors: Chiara Agrati,1Veronica Bordoni,1Alessandra Sacchi,1Nicola Petrosillo,1Emanuele Nicastri,1Franca Del Nonno,1Gianpiero D’Offizi,1Fabrizio Palmieri,1Luisa Marchioni,1Maria Rosaria Capobianchi,1Andrea Antinori,1Giuseppe Ippolito,1 and Michele Bibas1 Mediterr J Hematol Infect Dis. 2021; 13(1): e2021016.Published online 2021 Mar 1. doi: 10.4084/MJHID.2021.016 […]
Close relatives of MERS-CoV in bats use ACE2 as their functional receptors
Authors: Qing Xiong, View ORCID , , ei Cao, Chengbao Ma, Chen Liu, Junyu Si, Peng Liu, Mengxue Gu, Chunli Wang, Lulu Shi, Fei Tong, Meiling Huang, Jing Li, Chufeng Zhao, Chao Shen, Yu Chen, Huabin Zhao, Ke Lan, Xiangxi Wang, Huan Yan Summary Middle East Respiratory Syndrome coronavirus (MERS-CoV) and several bat coronaviruses employ Dipeptidyl peptidase-4 (DPP4) as […]
Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs
Authors: Taejoon Won, Megan K. Wood, David M. Hughes, Monica V. Talor, Zexu Ma Jowaly Schneider, et al. Published:January 12, 2022DOI:https://doi.org/10.1016/j.ebiom.2022.103812 Background Thromboembolism is a life-threatening manifestation of coronavirus disease […]
Elevated Expression of Serum Endothelial Cell Adhesion Molecules in COVID-19 Patients
Authos: Ming Tong,1Yu Jiang,2Da Xia,3Ying Xiong,3Qing Zheng,4Fang Chen,2Lianhong Zou,2Wen Xiao,2 and Yimin Zhu2 J Infect Dis. 2020 Sep 15; 222(6): 894–898.Published online 2020 Jun 24. doi: 10.1093/infdis/jiaa349 PMCID: PMC7337874PMID: 32582936 Abstract In a retrospective study of 39 […]
What Role does Endothelial Infection Play in SARS-CoV-2 Infection?
Authors: By Dr. Liji Thomas, MD Reviewed by Emily Henderson, B.Sc. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause inflammatory lung disease, including clot formation and hyper-permeability of the lung […]
Spike Proteins, COVID-19, and Vaccines
A new study further elucidates the role of spike proteins in COVID-19. Authors: Steven Novella May 5, 2021 A recent study looks at the effects of the SARS-CoV-2 spike proteins, showing […]
The novel coronavirus’ spike protein plays additional key role in illness
Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease April 30, 2021 LA JOLLA—Scientists have known for a while that SARS-CoV-2’s distinctive […]
‘We Made a Big Mistake’ — COVID Vaccine Spike Protein Travels From Injection Site, Can Cause Organ Damage
Authors: Children’s Health Defense COVID vaccine researchers had previously assumed mRNA COVID vaccines would behave like traditional vaccines. The vaccine’s spike protein — responsible for infection and its most severe symptoms — […]
Review of COVID-19, part 1: Abdominal manifestations in adults and multisystem inflammatory syndrome in children
Authors: Devaraju Kanmaniraja,a,⁎ Jessica Kurian,a Justin Holder,a Molly Somberg Gunther,a Victoria Chernyak,b Kevin Hsu,a Jimmy Lee,a Andrew Mcclelland,a Shira E. Slasky,a Jenna Le,a and Zina J. Riccia Abstract The coronavirus disease 2019 (COVID -19) pandemic caused by the novel severe acute […]